Results 171 to 180 of about 240,662 (294)
Identifying prognostic targets in metastatic prostate cancer beyond AR
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng+13 more
wiley +1 more source
A deep learning and digital archaeology approach for mosquito repellent discovery. [PDF]
Wei JN+15 more
europepmc +1 more source
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada+3 more
wiley +1 more source
Evaluation of the nutritional value and active compounds of commercial and non-commercial oilseed meals. [PDF]
Mollaei S, Hosseini-Nami SM, Hazrati S.
europepmc +1 more source
Auranofin, an Anti-Rheumatic Gold Compound, Modulates Apoptosis by Elevating the Intracellular Calcium Concentration ([Ca2+]i) in MCF-7 Breast Cancer Cells [PDF]
Elizabeth Varghese, Dietrich Büsselberg
openalex +1 more source
Earthing effects on mitochondrial function: ATP production and ROS generation
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley +1 more source
Neonicotinoid-Induced Cytotoxicity: Insights into Cellular Mechanisms and Health Risks. [PDF]
Ma Y, Wang Q.
europepmc +1 more source