Results 201 to 210 of about 235,164 (293)

Lion's Mane Mushroom (<i>Hericium erinaceus</i>): A Neuroprotective Fungus with Antioxidant, Anti-Inflammatory, and Antimicrobial Potential-A Narrative Review. [PDF]

Nutrients
Contato AG, Conte-Junior CA.
europepmc   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Recent Advancements Towards the Use of Vitamin D Isoforms and the Development of Their Synthetic Analogues as New Therapeutics. [PDF]

Biomedicines
Patel R, Nandini, Kharkwal H, Saha M, Sankaranarayanan M, Sharma S, Chander S.   +6 more
europepmc   +1 more source

232 CALCIFICATIONS IN OSTEOARTHRITIC HUMAN ARTICULAR CARTILAGE: ASSESSMENT OF CALCIUM COMPOUNDS THROUGH AN EX VIVO INVESTIGATION BASED ON XANES SPECTROSCOPY USING SYNCHROTRON RADIATION

, 2010
Christopher D. Nguyen, Hang‐Korng Ea, Dominique Thiaudière, Solenn Réguer, Didier Hannouche, Michel Daudon, Frédéric Lioté, D. Bazin   +7 more
openalex   +1 more source

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

FEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada, Kouhei Ohtani, Pushpa Kiran Gullapalli, Kazuhiko Ishikawa   +3 more
wiley   +1 more source

Synthesis of Heteroleptic Amidinato Calcium Halides via the In-Situ Grignard Addition Method (iGAM) Complementing the Metalation of Amidines. [PDF]

Chemistry
Sengupta S, Broek M, Köhler P, Westerhausen M.   +3 more
europepmc   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

Gadolinium in the Environment: A Double-Edged Sword for Plant Growth and Ecosystem Stability. [PDF]

Metabolites
Tomczuk M, Godlewska-Żyłkiewicz B, Bajguz A.   +2 more
europepmc   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source

Synthesis, Molecular Docking and Biological Evaluation of A-Ring-Carborane-Vitamin D Analogues. [PDF]

Molecules
Otero R, Seoane S, Fernández-Domínguez X, Bourguet M, Cianférani S, Peluso-Iltis C, Maestro MA, Pérez-Fernández R, Rochel N, Mouriño A.   +9 more
europepmc   +1 more source