Results 211 to 220 of about 265,121 (267)

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Glutamate Receptor Agonists as Triggers of Neurotoxicity: Decoding Pathways of Five Neurotoxins and Potential Therapeutic Targets. [PDF]

ACS Omega
Turcatel GA, Moura S.
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Controls of Polymorphism and Morphology of Calcium Carbonate Compounds Formed by Crystallizing Amorphous Calcium Carbonate Hydrate

, 1994
Yoshiyuki Kojima, Akio KAWANOBE, Tamotsu Yasue, Y. Arai   +3 more
openalex   +2 more sources

Integrating Experimental and Computational Approaches to Cardioprotection: Vascular Reactivity, Molecular Docking, and ADMET Modeling of <i>Melicoccus bijugatus</i> (Guinep). [PDF]

Int J Mol Sci
Logan K, Palacios J, Lopez S, Gray W, Nwokocha CR.   +4 more
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Modification of the Calcium Silicate Hydrate's DNA to Enhance its Mechanical Properties by Different Interactions with Aptes Compound

Carlos A. Orozco, Eduardo Duque-Redondo, Xabier M. Aretxabaleta, Hegoi Manzano, Paulo JM Monteiro   +4 more
openalex   +1 more source

Development and validation of combined in vitro and in vivo assays for evaluating the efficacy of strontium-chelating compounds. [PDF]

Sci Rep
Varga N, Pomozi V, Kozák E, Erdei Z, Tóth S, Kutás A, Mucsi Z, Rapi Z, Kovács B, Matuscsák A, Bánhídi O, Váradi C, Rácz T, Német K, Viskolcz B, Szepesi Á.   +15 more
europepmc   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

A Design of Experiment (DoE) Approach to Evaluate the Recyclability of a Polypropylene Copolymer in Medical Technology Under the Aspect of Additive Composition. [PDF]

Polymers (Basel)
Espelage N, Susoff ML, Schröder C, Blömer P, Petersen S.   +4 more
europepmc   +1 more source