Results 221 to 230 of about 265,121 (267)

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Fermented Chinese Herbs Improved Egg Production, Egg Shell Quality, and Egg Yolk Cholesterol of Laying Hens by Regulating Estrogen, Lipid Metabolism, and Calcium Metabolism. [PDF]

Animals (Basel)
Liu X, He Y, Cao Y, Wang X, Yang Y, Song J.   +5 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

<i>In Vivo</i> and <i>In Silico</i> Evaluation of a Polyphenol Fraction Extracted From <i>Argania spinosa</i> L. Press-Cake Against Ethylene Glycol-Induced Calcium Oxalate Urolithiasis in Rats: Biochemical, Histopathological, and Molecular Modeling Analyses. [PDF]

Food Sci Nutr
El Oumari FE, Hmamou A, Elrherabi A, Mammate N, El Fadili M, El Fatmi H, Belchkar S, Nasr FA, Al-Zharani M, Qurtam AA, Bousta D, Houssaini TS.   +11 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Repurposing 1,4-Dihydropyridine Scaffold: 4-Imidazo[2,1-<i>b</i>]thiazole-Derivatives from Calcium Entry Blockers to a New Approach for Gut Dysfunctional Motility. [PDF]

Pharmaceuticals (Basel)
Camarda L, Corazza I, Locatelli A, Leoni A, Frosini M, Budriesi R, Carosati E, Santini A, Montagnani M, Marzetti C, Mattioli LB.   +10 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Preparation and characterisation of calcium oxide from gypsum based compound for transesterification of waste cooking oil [PDF]

, 2018
Ramachandran Neshabran
openalex  

Assessment of Essential Nutrients, Bioactive Compounds, and Antioxidant Activity in the Leaves and Fruits of Chinese Olive (<i>Canarium album</i> (Lour.) DC.) Cultivars. [PDF]

Food Sci Nutr
Zhuang Q, Tan X, Ma P, Lai D, Shao X, Lai R, Xiao W.   +6 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source