Results 101 to 110 of about 44,944 (236)
Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report
Allergy, EarlyView.ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter +19 more
wiley +1 more source
Calcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion [PDF]
, 2015 Intra-endolysosomal Ca(2+) release is required for endolysosomal membrane fusion with intracellular organelles. However, the molecular mechanisms for intra-endolysosomal Ca(2+) release and the downstream Ca(2+) targets involved in the fusion remain ...
Baars +70 more
core +1 more source
Artificial Organs, EarlyView.This study reviews three adverse events during single donor platelet collection using root cause analysis. Causes included human error, equipment defects, and procedural lapses. Though all donors fully recovered, the incidents underscore the need for strict SOP adherence, staff training, and donor safety to maintain trust and donation retention.
Bhagyashri Surve +4 more
wiley +1 more source
Anuradhapura Medical Journal, 2013 We report on a 19-year-old boy with visible muscle spasms admitted to the hospitals 24 hours after spider bite. He was treated effectively with intravenous calcium gluconate followed by oral calcium supplements and made a full recovery 48 hours after the
NP Dinamithra +3 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu +4 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Kinases phosphorylate ion channels, but their noncatalytic roles via protein–protein interactions (PPI) are less understood. Here, we identified the peptidomimetic ZL141 to characterize the PPI between GSK3β and Nav1.6, revealing a noncatalytic role for GSK3β in regulating Nav1.6 currents and neuronal excitability ...
Aditya K. Singh +19 more
wiley +1 more source
Cell Proliferation, EarlyView.By assembling cortical‐hypothalamic circuits, we show that cortical input protects hypothalamic neurons from fatty acid‐induced damage, which activates PGC1α to boost mitochondrial function. This reveals a cortico‐hypothalamic axis that defends against metabolic stress.
Mengdan Tao +10 more
wiley +1 more source
Dentifrices for preventing erosive tooth wear: An in vitro comparative study
European Journal of Oral Sciences, EarlyView.Abstract Erosive tooth wear is a progressive condition that compromises enamel structure and requires preventive strategies. This in vitro study aimed to compare the protective effects of fluoride‐based dentifrices containing various bioactive agents on sound enamel subjected to simulated erosive–abrasive challenges.
Juliellen Luiz da Cunha +6 more
wiley +1 more source
Journal of Craniovertebral Junction and Spine, 2016 Epidural injection of steroid is given for back pain resistant to other conservative management. Normal saline (NS) is used as diluent in 80 mg methylprednisolone and a local anesthetic. Due to a similar looking ampoule of NS and potassium chloride (KCl),
Rahul Ranjan +3 more
doaj +1 more source
Possible hazardous effects of hydrofluoric acid and recommendations for treatment approach: a review [PDF]
, 2018 Hydrofluoric acid (HF) is commonly used for conditioning the glass ceramics either prior to cementation or for intraoral repair in prosthetic and restorative dentistry.
Allahbeickaraghi, Arezo +2 more
core