Results 91 to 100 of about 352,898 (311)

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

A Contribution to the Study of Calcium Metabolism [PDF]

, 1908
S. W. Patterson
openalex   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

METABOLIC STUDIES IN PARALYTIC ACUTE ANTERIOR POLIOMYELITIS. IV. EFFECTS OF TESTOSTERONE PROPIONATE AND ESTRADIOL BENZOATE ON CALCIUM, PHOSPHORUS, NITROGEN, CREATINE AND ELECTROLYTE METABOLISM 1 [PDF]

, 1957
G. Donald Whedon, Ephraim Shorr, Vincent Toscani, Estelle Stevens   +3 more
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Are Painted Turtles (Chrysemys picta) Resilient to the Potential Impact of Climate Change on Vitamin D via Overgrown Floating Vegetation?

Diversity
Floating aquatic vegetation and algal blooms are increasing with global warming, potentially reducing UVB exposure and, consequently, vitamin D (vit-D) synthesis in freshwater turtles. Vit-D mediates calcium metabolism and overall health, yet the effects
Nicholas E. Topping, Nicole Valenzuela
doaj   +1 more source

The Mediation Effect of Peripheral Biomarkers of Calcium Metabolism and Chronotypes in Bipolar Disorder Psychopathology. [PDF]

Metabolites, 2022
de Filippis R, D'Angelo M, Carbone EA, De Fazio P, Steardo L.   +4 more
europepmc   +1 more source

CALCIUM METABOLISM IN A CASE OF INFANTILE TETANY [PDF]

, 1911
Howard D. Haskins, H. J. Gerstenberger
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Serum Vitamin D in Common Non-Metabolic Disorders: Results of Patients’ Survey at Public Hospitals of Karachi

Journal of the Dow University of Health Sciences, 2009
Objective: To analyse different causative factors leading to oral cancer. Study Design: Descriptive type of study.Setting: This study was conducted at the department of E.N.T, DUHS, Karachi. Study Period: From Jan 2008, to October 2008.
M. Akhter Baig, S. Mujahid Humail, Munawar Iqbal, Nayer ul Islam   +3 more
doaj   +2 more sources