Results 101 to 110 of about 2,715,719 (363)

Time-of-flight secondary ion mass spectrometry-based molecular distribution distinguishing healthy and osteoarthritic human cartilage [PDF]

, 2013
Osteoarthritis (OA) is a pathology that ultimately causes joint destruction. The cartilage is one of the principal affected tissues. Alterations in the lipid mediators and an imbalance in the metabolism of cells that form the cartilage (chondrocytes) have been described as contributors to the OA development.
arxiv   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Prebiotic effects: metabolic and health benefits [PDF]

, 2010
The different compartments of the gastrointestinal tract are inhabited by populations of micro-organisms. By far the most important predominant populations are in the colon where a true symbiosis with the host exists that is a key for well-being and ...
Agnes Meheust, Anne L. McCartney, Audrey M. Neyrinck, Balsari, Ben, Bernd Stahl, Bernhard Watzl, Blaut, Brommage, Caderni, Caers, Cashman, Cashman, Chassard, Coudray, Cummings, Danielle Wolvers, de Vrese, Dughera, Engelhardt, Fava, Francisco Guarner, Franck, Frederique Respondek, Gibson, Girrbach, Glenn R. Gibson, Gray, Griffin, Hanai, Hania Szajewska, Harmsen, Hawthorne, Hudson, Hughes, Hussey, Ian Rowland, Irvine, Irvine, Kanauchi, Kelly, Kevin Whelan, Kim, Klobukowski, Kobayashi, Laurent Léotoing, Lesley Hoyles, Levitt, Lien do, Macfarlane, Macfarlane, Marcel Roberfroid, Marie-Jeanne Davicco, Mathey, Morand, Murphy, Nathalie M. Delzenne, Ng, O'Connor, O'May, Ohta, Ohta, Patrice D. Cani, Perrin, Pierre, Quigley, Rayssiguier, Reddy, Remesy, Reshef, Reuter, Richardson, Roberfroid, Roberfroid, Roberfroid, Roberfroid, Roberfroid, Robert Rastall, Rondon, Rowland, Sakaguchi, Schaafsma, Sellon, Siong, Suau, Taper, van Dokkum, Veronique Coxam, Vulevic, Wada, Walker, Wilson, Yohann Wittrant, Zoetendal, Zoetendal   +94 more
core   +2 more sources

Orofacial Features, Oral Health-Related Quality of Life, and Exposure to Bullying in Osteogenesis Imperfecta: A Cross-Sectional Study

Children
Background/Objectives: Osteogenesis imperfecta (OI) is a rare genetic disease that is responsible for bone fragility, but also for dental malocclusions and dentinogenesis imperfecta (DI). The aim of this study was to assess whether the severity of dental
Alice Broutin, Jean-Pierre Salles, Valérie Porquet-Bordes, Thomas Edouard, Frédéric Vaysse, Emmanuelle Noirrit-Esclassan   +5 more
doaj   +1 more source

Information and long term memory in calcium signals [PDF]

arXiv, 2015
Unicellular organisms are open metabolic systems that need to process information about their external environment in order to survive. In most types of tissues and organisms, cells use calcium signaling to carry information from the extracellular side of the plasma membrane to the different metabolic targets of their internal medium.
arxiv  

Computational models of astrocyte function at glutamatergic synapses [PDF]

New Technologies for Glutamate Interactions: Neurons and Glia, edited by Maria Kukley, 2024, Springer Protocols
At tripartite synapses, astrocytes are in close contact with neurons and contribute to various functions, from synaptic transmission, maintenance of ion homeostasis and glutamate uptake to metabolism. However, disentangling the precise contribution of astrocytes to those phenomena and the underlying biochemical mechanisms is remarkably challenging ...
arxiv   +1 more source

Regulation of store-operated calcium entry [PDF]

arXiv, 2023
Plasma membrane calcium influx through ion channels is crucial for many events in cellular physiology. Cell surface stimuli lead to the production of inositol 1,4,5-trisphosphate (IP3), which binds to IP3 receptors in the endoplasmic reticulum (ER) to release calcium pools from the ER lumen.
arxiv  

Calcium Co-regulates Oxidative Metabolism and ATP Synthase-dependent Respiration in Pancreatic Beta Cells

Journal of Biological Chemistry, 2014
Background: Nutrients stimulate calcium dependent activation of energy metabolism, in pancreatic beta cells. Results: Glucose-induced ATP synthase-dependent respiration is strictly calcium-dependent, with little or no effect of calcium on the NAD(P)H ...
U. De Marchi, Jonathan Thévenet, Aurélie Hermant, E. Dioum, A. Wiederkehr   +4 more
semanticscholar   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Identification of Three Early Phases of Cell-Fate Determination during Osteogenic and Adipogenic Differentiation by Transcription Factor Dynamics

Stem Cell Reports, 2017
Summary: Age-related skeletal degeneration in patients with osteoporosis is characterized by decreased bone mass and occurs concomitant with an increase in bone marrow adipocytes.
Jeroen van de Peppel, Tanja Strini, Julia Tilburg, Hans Westerhoff, Andre J. van Wijnen, Johannes P. van Leeuwen   +5 more
doaj