Results 111 to 120 of about 2,493,792 (352)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Serum Vitamin D in Common Non-Metabolic Disorders: Results of Patients’ Survey at Public Hospitals of Karachi

open access: yesJournal of the Dow University of Health Sciences, 2009
Objective: To analyse different causative factors leading to oral cancer. Study Design: Descriptive type of study.Setting: This study was conducted at the department of E.N.T, DUHS, Karachi. Study Period: From Jan 2008, to October 2008.
M. Akhter Baig   +3 more
doaj   +2 more sources

Structural and functional features of reparative osteogenesis under the influence of natural healing factors

open access: yesJournal of Education, Health and Sport, 2015
Pavlenko K. V., Nasibullin B. A., Uvarova Ye. B., Gozhenko A. I. Структурно-функциональные особенности репаративного остеогенеза под влиянием природных лечебных факторов = Structural and functional features of reparative osteogenesis under the influence ...
K. V. Pavlenko   +3 more
doaj  

Association of germline variants in the ZFX gene with primary hyperparathyroidism.

open access: yesPLoS ONE
Somatic variants in the ZFX gene have been found in human sporadic parathyroid adenomas. This gene encodes a transcriptional factor recently described as a transcriptional activator in multiple types of human tumors. We present the clinical and molecular
Ainhoa Camille Aranaga-Decori   +7 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Calcium deposition in chicken eggshells: role of host genetics and gut microbiota

open access: yesPoultry Science
: Eggshell is predominantly composed of calcium carbonate, making up about 95% of its composition. Eggshell quality is closely related to the amount of calcium deposition in the shell, which requires chickens to maintain a robust state of calcium ...
Jiaming Jin   +10 more
doaj   +1 more source

Applications of Metabolomics in Calcium Metabolism Disorders in Humans. [PDF]

open access: yesInt J Mol Sci, 2022
Podgórska B   +7 more
europepmc   +1 more source

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