Results 121 to 130 of about 2,715,719 (363)

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Do Flame Retardants Promote Vitamin D Deficiency? [PDF]

open access: yes, 2014
Vitamin D deficiency in the Unites States has become more prevalent in recent years. Research has shown that environmental chemicals such as flame-retardants induce hepatic enzymes in the cytochrome P450 family such as CYP24 and CYP3A that are important ...
Petteruti, Audrey
core   +2 more sources

Physiology of calcium metabolism in kidneys

open access: yesОжирение и метаболизм, 2011
Biologic functions of calcium include maintenance of skeletal integrity, signal transduction, cell permeability, excitation-secretion and excitation-contraction coupling and cell fertilization.

doaj   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Mechanisms of water-salt metabolism disturbances in dogs subjected to six month hypokinesia [PDF]

open access: yes
Water-salt metabolism in dogs during prolonged restricted motor activity (hypokinesia) was investigated. It was found that hydration occurred and fluid was redistributed between the extra- and intra-cellular sectors. Also, electrolyte excretion rose, and
Ilyushko, N. A.   +5 more
core   +1 more source

Vitamin D and calcium metabolism in horses in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Institute of Veterinary, Animal and Biomedical Sciences (IVABS), Massey University, Manawatū, New Zealand [PDF]

open access: yes, 2016
The physiology of vitamin D in horses has not been studied in great depth. Few studies on vitamin D metabolites (25OHD2, 25OHD3, and 1,25(OH)2D) and their relationship to other serum analytes exist. In addition, some studies suggest that equine vitamin D
Azarpeykan, Sara
core  

Vitamin D: Newer Concepts of Its Metabolism and Function at the Basic and Clinical Level. [PDF]

open access: yes, 2020
The interest in vitamin D continues unabated with thousands of publications contributing to a vast and growing literature each year. It is widely recognized that the vitamin D receptor (VDR) and the enzymes that metabolize vitamin D are found in many ...
Bikle, Daniel D
core   +1 more source

Supplementation of the Combination of Quercetin and Vitamin E Alleviates the Effects of Heat Stress on the Uterine Function and Hormone Synthesis in Laying Hens

open access: yesAnimals
Chickens are sensitive to heat stress because their capacity to dissipate body heat is low. Hence, in chickens, excessive ambient temperature negatively influences their reproductive performance and health.
Xueqing Cao   +8 more
doaj   +1 more source

Cloning and functional analysis of BMP3 in the pearl oyster (Pinctada fucata)

open access: yesJournal of Applied Animal Research, 2019
Bone morphogenetic proteins (BMPs) are multifunctional secreted cytokines that play important roles in bone formation. In the present study, a homologous BMP3 gene was identified from Pinctada fucata (PfBMP3). PfBMP3 was 2710 bp length, contained 1470 bp
Sigang Fan   +3 more
doaj   +1 more source

A pharmacokinetic model of lead absorption and calcium competitive dynamics [PDF]

open access: yesarXiv, 2019
Lead is a naturally-occurring element. It has been known to man for a long time, and it is one of the longest established poisons. The current consensus is that no level of lead exposure should be deemed "safe." New evidence regarding the blood levels at which morbidities occur has prompted the CDC to reduce the screening guideline of 10 $\mu$g/dl to 2
arxiv  

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