Results 71 to 80 of about 352,898 (311)

Organic phosphate but not inorganic phosphate regulates Fgf23 expression through MAPK and TGF-ꞵ signaling

open access: yesiScience
Summary: One of the main regulators of phosphate homeostasis is fibroblast growth factor 23 (FGF23), secreted by osteocytes. The effects of organic versus inorganic dietary phosphate on this homeostasis are unclear.
Danielle M.A. Ratsma   +5 more
doaj  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

AUTOSOMAL DOMINANT HYPOCALCEMIA (HYPOPARATHYROIDISM) TYPES 1 AND 2

open access: yesFrontiers in Physiology, 2016
Extracellular calcium is essential for life and its concentration in the blood is maintained within a narrow range. This is achieved by a feedback loop that receives input from the calcium-sensing receptor (CASR), expressed on the surface of parathyroid
Kelly Lauter Roszko   +2 more
doaj   +1 more source

Studies in calcium metabolism [PDF]

open access: green, 1928
Corbet Page Stewart, G. H. Percival
openalex   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Structural and functional features of reparative osteogenesis under the influence of natural healing factors

open access: yesJournal of Education, Health and Sport, 2015
Pavlenko K. V., Nasibullin B. A., Uvarova Ye. B., Gozhenko A. I. Структурно-функциональные особенности репаративного остеогенеза под влиянием природных лечебных факторов = Structural and functional features of reparative osteogenesis under the influence ...
K. V. Pavlenko   +3 more
doaj  

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Effect of dietary cation–anion difference on ruminal metabolism, total apparent digestibility, blood and renal acid–base regulation in lactating dairy cows

open access: yesAnimal, 2016
The present study aimed to evaluate the effect of dietary cation–anion difference (DCAD) on ruminal fermentation, total apparent digestibility, blood and renal metabolism of lactating dairy cows.
C.M.M.R. Martins   +4 more
doaj  

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