Results 81 to 90 of about 2,715,719 (363)

Longitudinal Analysis of Calcium Supplementation Preventing Bone Mass Loss in Females [PDF]

, 2012
Calcium is an important nutrient for metabolism of bones (Greer & Krebs, 2006). This study hypothesizes that consuming calcium supplements for twenty years decreases women’s risk of developing osteoporosis.
Nicola, Piilani
core   +1 more source

Expression of Renal Vitamin D and Phosphatonin-Related Genes in a Sheep Model of Osteoporosis

Animals, 2021
Osteoporosis is a significant public health issue around the world, with post-menopausal osteoporosis due to estrogen deficiency resulting in approximately ¾ of cases. In this study, 18 aged Merino ewes were ovariectomized, and 10 were controls. Three of
Keren E. Dittmer, Anastasia Chernyavtseva, Jonathan C. Marshall, Diana Cabrera, Frances M. Wolber, Marlena Kruger   +5 more
doaj   +1 more source

Parameters for calcium metabolism in women with polycystic ovary syndrome who undergo clomiphene citrate stimulation: a prospective cohort study.

European Journal of Endocrinology, 2012
OBJECTIVE To evaluate whether parameters for calcium metabolism were associated with characteristics of polycystic ovary syndrome (PCOS). DESIGN A prospective cohort study.
Johannes Ott, Luna Wattar, Christine Kurz, Rudolf Seemann, Johannes C. Huber, Klaus Mayerhofer, Elisabeth Vytiska-Binstorfer   +6 more
semanticscholar   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

The Mitochondrial Ca(2+) Uniporter: Structure, Function, and Pharmacology. [PDF]

, 2017
Mitochondrial Ca(2+) uptake is crucial for an array of cellular functions while an imbalance can elicit cell death. In this chapter, we briefly reviewed the various modes of mitochondrial Ca(2+) uptake and our current understanding of mitochondrial Ca(2+)
A Quintana, A Raffaello, A Rasola, A Tosatto, A Varadi, AA Rowland, AI Tarasov, AN Antony, AR Marks, B Chance, B Glancy, B Moreau, C Giorgi, C Petrungaro, CC Mendes, CD Lobaton, CV Logan, CV Nicchitta, D Chaudhuri, D Chaudhuri, D De Stefani, D Jiang, D Lewis-Smith, D Tomar, D Vecellio Reane, DA Cox, DD Hall, DG Nicholls, DJ Pagliarini, E Carafoli, E Carafoli, E Kovacs-Bogdan, E Murphy, E Noack, E Rapizzi, F Fieni, F Fieni, F Perocchi, FD Vasington, G Bathori, G Beutner, G Beutner, G Csordas, G Csordas, G Csordas, G Csordas, G Csordas, G Csordas, G Csordas, G Czirjak, G Giannini, G Hajnoczky, G Hajnoczky, G Huang, G Michels, G Munch, G Szabadkai, G Szalai, G Szanda, G Szanda, GA Rutter, GC Sparagna, GD Schellenberg, GL Becker, H Vais, HF Deluca, I Bogeski, I Drago, I Zimanyi, J Matesanz-Isabel, J Nakai, J O-Uchi, J O-Uchi, J O-Uchi, J Qiu, J Santo-Domingo, J Schwartz, JD Martell, JG McCormack, JL Harrington, JM Baughman, JQ Kwong, JS Marchant, JT Lanner, JW Putney Jr, K Mallilankaraman, K Mallilankaraman, K Oxenoid, KJ Kamer, KM Holmstrom, L Buntinas, L Hymel, L Mela, L Wang, LH Jeyakumar, LK Seidlmayer, LS Jouaville, M Boerries, M Crompton, M Crompton, M Giacomello, M Giacomello, M Hoth, M Hoth, M Montero, M Montero, M Murgia, M Patron, M Plovanich, M Salvi, M Sastrasinh, MA Matlib, MF Tsai, MK Park, ML Joiner, ML Joiner, ML Litsky, ML Olson, MR Alam, MR Duchen, N MacQuaide, NE Hoffman, NJ Dolman, P Bernardi, P Koncz, P Pinton, PJ Doonan, PS Brookes, R Amann, R Jakob, R Malli, R Malli, R Perez-Campo, R Rizzuto, R Rizzuto, R Rizzuto, R Rizzuto, RM Denton, RM Denton, RM Denton, RS Sohal, S Feng, S Fuente de la, S Grimm, S Marchi, S Shanmughapriya, S Xu, SA Thayer, SS Lam, SY Ryu, T Pozzan, T Rharass, T Yamamoto, TE Gunter, TE Gunter, TE Gunter, TS Luongo, V Hung, V Paupe, VK Sharma, W Tan, WL Ying, X Pan, X Quan, Y Kirichok, Y Lee, Y Sancak, Y Wu   +167 more
core   +2 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Outcomes of orthopedic surgery in a cohort of 49 patients with X-linked hypophosphatemic rickets (XLHR)

Endocrine Connections, 2017
Background: X-linked hypophosphatemic rickets (XLHR) is due to mutations in PHEX leading to unregulated production of FGF23 and hypophosphatemia. XLHR is characterized by leg bowing of variable severity.
A Gizard, A Rothenbuhler, Z Pejin, G Finidori, C Glorion, B de Billy, A Linglart, P Wicart   +7 more
doaj   +1 more source

The role of calcium metabolism disorders in the formation of different density calculi with calcium oxalate nephrolithiasis

Инновационная медицина Кубани, 2021
Objective To investigate the relationship between calcium metabolism disorders, stone formation inhibitor levels and stone density in primary and recurrent calcium-oxalate nephrolithiasis.Material and Methods Sixty nine patients with urolithiasis were ...
A. A. Budanov, V. L. Medvedev, A. N. Kurzanov, A. A. Basov, E. S. Gazimiev   +4 more
doaj   +1 more source

Mitochondrial metabolism and cancer

Cell Research, 2017
Glycolysis has long been considered as the major metabolic process for energy production and anabolic growth in cancer cells. Although such a view has been instrumental for the development of powerful imaging tools that are still used in the clinics, it ...
P. Porporato, N. Filigheddu, J. B. Pedro, G. Kroemer, L. Galluzzi   +4 more
semanticscholar   +1 more source

An Update on Vitamin D Metabolism

International Journal of Molecular Sciences, 2020
Vitamin D is a steroid hormone classically involved in the calcium metabolism and bone homeostasis. Recently, new and interesting aspects of vitamin D metabolism has been elucidated, namely the special role of the skin, the metabolic control of liver ...
F. Saponaro, A. Saba, R. Zucchi
semanticscholar   +1 more source