Results 11 to 20 of about 380,936 (322)
Applications of Metabolomics in Calcium Metabolism Disorders in Humans. [PDF]
Int J Mol Sci, 2022 The pathogenesis of the disorders of calcium metabolism is not fully understood. This review discusses the studies in which metabolomics was applied in this area. Indeed, metabolomics could play an essential role in discovering biomarkers and elucidating pathological mechanisms.
Podgórska B +7 more
europepmc +5 more sources
Disorders of Calcium Metabolism: Hypocalcemia and Hypercalcemia [PDF]
Cureus, 2021 Calcium (Ca+2) is a divalent cation that plays a critical role in numerous body functions such as skeletal mineralization, signal transduction, nerve conduction, muscle contraction, and blood coagulation. Ca+2 metabolism is linked to magnesium (Mg+2) and phosphate metabolism.
M. Tinawi
semanticscholar +6 more sources
Five patients with disorders of calcium metabolism presented with GCM2 gene variants [PDF]
Scientific Reports, 2021 The GCM2 gene encodes a transcription factor predominantly expressed in parathyroid cells that is known to be critical for development, proliferation and maintenance of the parathyroid cells.
Alejandro García-Castaño +18 more
doaj +3 more sources
Disorders of Calcium and Phosphorus Metabolism and the Proteomics/Metabolomics-Based Research
Frontiers in Cell and Developmental Biology, 2020 Since calcium and phosphorus play vital roles in a multitude of physiologic systems, disorders of calcium and phosphorus metabolism always lead to severe consequences such as skeletal-related and cardiovascular morbidity, or even life-threatening ...
Meiheng Sun +27 more
doaj +4 more sources
Genetics of monogenic disorders of calcium and bone metabolism [PDF]
Clinical Endocrinology, 2021 AbstractDisorders of calcium homeostasis are the most frequent metabolic bone and mineral disease encountered by endocrinologists. These disorders usually manifest as primary hyperparathyroidism (PHPT) or hypoparathyroidism (HP), which have a monogenic aetiology in 5%–10% of cases, and may occur as an isolated endocrinopathy, or as part of a complex ...
Paul J. Newey +3 more
semanticscholar +6 more sources
Genetic Disorders of Calcium and Phosphorus Metabolism [PDF]
Endocrines, 2022 In this review, we describe genetic mutations affecting metabolic pathways of calcium and phosphorus homeostasis. Calcium and phosphorus homeostasis has tight hormonal regulation by three major hormones: vitamin D, parathyroid hormone (PTH) and ...
Assia Miller +4 more
doaj +2 more sources
International Journal of Molecular Sciences, 2022 Bone contributes to supporting the body, protecting the central nervous system and other organs, hematopoiesis, the regulation of mineral metabolism (mainly calcium and phosphate), and assists in respiration. Bone has many functions in the body. Recently,
Y. Takashi, Daiji Kawanami
semanticscholar +2 more sources
DIAGNOSTIC PROCEDURES IN DISORDERS OF CALCIUM METABOLISM [PDF]
Clinical Endocrinology, 1978 SUMMARYThe investigation of a patient with a suspected disorder of calcium metabolism is most rapidly and efficiently performed by observing a standard procedure, the initial stages of which are simple and mandatory, the later stages more complex and determined by the initial results and the depth of investigation required.
B. Nordin
openaire +3 more sources
Zaporožskij Medicinskij Žurnal, 2017 The processes in bone-mineral metabolism provide normal course of pregnancy, labour and fetus development, women with body weight deficiency are at risk reduction of bone tissue mineral density, progressing of osteopenia and osteoporosis.
L. P. Shelestova
doaj +2 more sources
Calcium-phosphate metabolism – selected disorders in children
Pediatric Endocrinology, Diabetes and MetabolismElżbieta Jakubowska-Pietkiewicz
doaj +2 more sources