Results 61 to 70 of about 793,657 (289)
Calcium can mobilize and activate myosin-VI [PDF]
Proceedings of the National Academy of Sciences, 2016 Significance The timing of motor protein activation is central to a broad range of cellular motile processes including endocytosis, cell division, and cancer cell migration. The cytoskeletal motor myosin-VI is involved in these processes and is the only myosin in the human genome shown to move toward the minus end of actin filaments ...
Christopher, Batters +4 more
openaire +2 more sources
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Tissue-specific expression of calcium channels [PDF]
, 1993 The high-voltage-activated calcium channel is a multimeric protein complex containing 1, 2/δ, β, and γ subunits. The 1 subunit is the ion conduction channel and contains the binding sites for calcium channel blockers and toxins.
Flockerzi, Veit +3 more
core +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer +11 more
wiley +1 more source
“CONSCIENCE ADHERENTS” REVISITED: NON-LGBT PRIDE PARADE PARTICIPANTS*
, 2018 Foundation stones in the resource mobilization theory of social movements are the notions of “conscience adherents” and “conscience constituents,” first introduced by McCarthy and Zald in 1977.
Wahlström, Mattias, +5 more
core +1 more source
Calcium Carbonate Suppresses Haem Toxicity Markers without Calcium Phosphate Side Effect on Colon Carcinogenesis [PDF]
, 2010 Red meat intake is associated with increased risk of colorectal cancer. We have previously shown that haemin, haemoglobin and red meat promote carcinogen-induced preneoplastic lesions, aberrant crypt foci, in the colon of rats.
Diane Bahuaud +13 more
core +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
The role of CaMKⅡδ in platelet activation mediated by thrombin and TRAP
Zhongguo shuxue zazhi[Objective] To investigate the role of calcium/calmodulin-dependent protein kinase Ⅱ delta (CaMKⅡδ) in platelet activation mediated by thrombin and thrombin receptor activator peptide (TRAP). [Methods] The CaMKⅡδ-specific inhibitor Hesperadin was used to
ZHAO Yafei +4 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Lysophosphatidic acid (LPA) is a bioactive phospholipid that acts as an agonist of six G protein-coupled receptors named LPA receptors (LPA1-6).
C. Ruzza +7 more
doaj +1 more source