Results 221 to 230 of about 1,131,166 (283)

Deciphering Anti‐Cancer Drug Efficacy Through Nanomechanical Vibrations in Living Gastric Cancer Organoids

open access: yesAdvanced Science, EarlyView.
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang   +10 more
wiley   +1 more source

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

open access: yesAdvanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi   +7 more
wiley   +1 more source

Mechanical properties and antibacterial efficacy against Streptococcus mutans biofilms of novel bioactive tooth root coatings in tooth-brushing simulation. [PDF]

open access: yesDent Mater
Almutairi N   +11 more
europepmc   +1 more source

Multifunctional PVP/PEG Hydrogel Coatings Functionalized with Taxifolin for Surface Modification of Titanium-Based Substrates. [PDF]

open access: yesInt J Mol Sci
Młyniec K   +7 more
europepmc   +1 more source

Current Options and Future Perspectives for Conversion Coatings on Biodegradable Magnesium Alloys to Control the Biodegradation Rate and Biological Features. [PDF]

open access: yesBiomimetics (Basel)
Manescu Paltanea V   +7 more
europepmc   +1 more source

Influence of spray stand-off distance, plasma intensity, and Ar/H<sub>2</sub> ratio, on the phase composition and microstructure of bismuth-containing 45S5 bioactive glass coatings deposited by atmospheric plasma spray (APS).

open access: yesResults Surf Interfaces
Clavijo-Mejía GA   +9 more
europepmc   +1 more source

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