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The Journal of Rheumatology
ObjectiveAcute and chronic calcium pyrophosphate (CPP) crystal arthritis is characterized by the presence of synovial CPP crystals within a clinically inflamed joint. CPP crystals may be situated intracellularly or extracellularly; however, the clinical significance of their location remains understudied.
David J. Harris +2 more
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ObjectiveAcute and chronic calcium pyrophosphate (CPP) crystal arthritis is characterized by the presence of synovial CPP crystals within a clinically inflamed joint. CPP crystals may be situated intracellularly or extracellularly; however, the clinical significance of their location remains understudied.
David J. Harris +2 more
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Pathophysiology of calcium pyrophosphate deposition
2016Calcium pyrophosphate (CPP) dihydrate crystals form extracellularly. Their formation requires sufficient extracellular inorganic pyrophosphate (ePPi), calcium, and pro-nucleating factors. As inorganic pyrophosphate (PPi) cannot cross cell membranes passively due to its large size, ePPi results either from hydrolysis of extracellular ATP by the enzyme ...
Abhishek Abhishek, Michael Doherty
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Treatment of calcium pyrophosphate deposition
2016The treatment of calcium pyrophosphate crystal deposition (CPPD) is mainly symptomatic. Acute calcium pyrophosphate (CPP) crystal synovitis should be treated with rest, local application of ice packs, joint aspiration, and/or intra-articular corticosteroid injection (once joint sepsis has been excluded).
Abhishek Abhishek, Michael Doherty
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Investigations of calcium pyrophosphate deposition
2016Joint aspiration and microscopic examination of the aspirated synovial fluid remains the gold standard for the diagnosis of calcium pyrophosphate crystal deposition (CPPD). If synovial fluid aspiration is not feasible, plain radiography and/or ultrasound scanning may be used to detect chondrocalcinosis (CC) which predominantly occurs due to calcium ...
Abhishek Abhishek, Michael Doherty
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Calcium pyrophosphate crystal chemistry
Arthritis & Rheumatism, 1976W E, Brown, T M, Gregory
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Calcium Pyrophosphate Deposition Pseudoabscess
JCR: Journal of Clinical Rheumatology, 2015Jen-Yee, Hong +4 more
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Calcium pyrophosphate deposition
British Journal of Hospital Medicine, 2014openaire +2 more sources
Ultrasound findings of calcium pyrophosphate deposition disease at metacarpophalangeal joints
Rheumatology, 2022Edoardo Cipolletta +2 more
exaly
[Arthropathies due to calcium pyrophosphates].
Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften, 1980Articular chondrocalcinosis results from the deposits of calcium pyrophosphate microcrystals in the articular hyalin and fibrocartilages, the synovium and at times the tendons. In our area it is seen most frequently as isolated cases in the elderly and may be asymptomatic.
G H, Fallet, A, Micheli
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