Results 1 to 10 of about 6,648 (299)

Prenols and prenoic acids in metabolism, disease, and aging [PDF]

open access: yesJournal of Lipid Research
Acyclic terpene derivatives are well-known as components of plant essential oils and insect hormones, yet their active biosynthesis also occurs in mammals.
Ignasi Bofill Verdaguer   +10 more
doaj   +2 more sources

Impact of the Warburg effect on nucleotide homeostasis in human retinal endothelial cells and its relevance to proliferative diabetic retinopathy [PDF]

open access: yesFrontiers in Pharmacology
PurposeWhile great progress has been made in screening methods and therapies for proliferative diabetic retinopathy (PDR), it is still a major cause of blindness.
Andrew Gregory   +14 more
doaj   +2 more sources

A universal polyphosphate kinase powers in vitro transcription [PDF]

open access: yesNature Communications
Polyphosphate kinases (PPKs) catalyze phosphoryl transfer between polyphosphates and nucleotides. Polyphosphates are a cost-effective source of phosphorylating power, making PPKs attractive enzymes for nucleotide production.
Ryusei Matsumoto   +5 more
doaj   +2 more sources

The prevalence and co-occurrence of emulsifiers, thickeners and stabilizers in food products on the Norwegian market [PDF]

open access: yesFood & Nutrition Research
Background: As the intake of food that has undergone substantial processing increases, the intake of common additives like Emulsifiers, Thickeners, and Stabilizers (ETSs) also increases.
Åsne Skram Trømborg   +3 more
doaj   +2 more sources

The NUDIX hydrolase NUDT5 influences purine nucleotide metabolism and thiopurine pharmacology [PDF]

open access: yesThe Journal of Clinical Investigation
Purine nucleotides are critical for nucleic acid synthesis, signaling, and cellular metabolism. Thiopurines (TPs), including 6-mercaptopurine and 6-thioguanine, are cornerstone agents for the treatment of acute lymphoblastic leukemia (ALL).
Leo Kager, Kaan Boztug
doaj   +2 more sources

Nucleoside Diphosphate Kinase Family: Evolutionary Analysis and Protective Role in Mitochondrial ROS Production [PDF]

open access: yesPlants
Nucleoside diphosphate kinase (NDPK) is a ubiquitous enzyme that maintains cellular nucleotide balance by catalyzing the transfer of phosphate groups between nucleoside diphosphates and triphosphates.
Douglas Jardim-Messeder   +4 more
doaj   +2 more sources

Oritavancin Diphosphate [PDF]

open access: yesHospital Pharmacy, 2014
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing ...
Dennis J, Cada, Danial E, Baker
openaire   +2 more sources

Inhibitors of the Cancer Target Ribonucleotide Reductase, Past and Present

open access: yesBiomolecules, 2022
Ribonucleotide reductase (RR) is an essential multi-subunit enzyme found in all living organisms; it catalyzes the rate-limiting step in dNTP synthesis, namely, the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates.
Sarah E. Huff   +2 more
doaj   +1 more source

Potentiating Vγ9Vδ2 T cell proliferation and assessing their cytotoxicity towards adherent cancer cells at the single cell level

open access: yesBiology Open, 2022
Vγ9Vδ2 T cells is the dominant γδ T cell subset in human blood. They are cytotoxic and activated by phosphoantigens whose concentrations are increased in cancer cells, making the cancer cells targets for Vγ9Vδ2 T cell immunotherapy.
Chenxiao Liu   +3 more
doaj   +1 more source

URIDINE DIPHOSPHATE ACETYLGLUCOSAMINE

open access: yesJournal of Biological Chemistry, 1953
Blanco y ...
Cabib, Enrico   +2 more
openaire   +6 more sources

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