Results 1 to 10 of about 6,648 (299)
Prenols and prenoic acids in metabolism, disease, and aging [PDF]
Acyclic terpene derivatives are well-known as components of plant essential oils and insect hormones, yet their active biosynthesis also occurs in mammals.
Ignasi Bofill Verdaguer +10 more
doaj +2 more sources
Impact of the Warburg effect on nucleotide homeostasis in human retinal endothelial cells and its relevance to proliferative diabetic retinopathy [PDF]
PurposeWhile great progress has been made in screening methods and therapies for proliferative diabetic retinopathy (PDR), it is still a major cause of blindness.
Andrew Gregory +14 more
doaj +2 more sources
A universal polyphosphate kinase powers in vitro transcription [PDF]
Polyphosphate kinases (PPKs) catalyze phosphoryl transfer between polyphosphates and nucleotides. Polyphosphates are a cost-effective source of phosphorylating power, making PPKs attractive enzymes for nucleotide production.
Ryusei Matsumoto +5 more
doaj +2 more sources
The prevalence and co-occurrence of emulsifiers, thickeners and stabilizers in food products on the Norwegian market [PDF]
Background: As the intake of food that has undergone substantial processing increases, the intake of common additives like Emulsifiers, Thickeners, and Stabilizers (ETSs) also increases.
Åsne Skram Trømborg +3 more
doaj +2 more sources
The NUDIX hydrolase NUDT5 influences purine nucleotide metabolism and thiopurine pharmacology [PDF]
Purine nucleotides are critical for nucleic acid synthesis, signaling, and cellular metabolism. Thiopurines (TPs), including 6-mercaptopurine and 6-thioguanine, are cornerstone agents for the treatment of acute lymphoblastic leukemia (ALL).
Leo Kager, Kaan Boztug
doaj +2 more sources
Nucleoside Diphosphate Kinase Family: Evolutionary Analysis and Protective Role in Mitochondrial ROS Production [PDF]
Nucleoside diphosphate kinase (NDPK) is a ubiquitous enzyme that maintains cellular nucleotide balance by catalyzing the transfer of phosphate groups between nucleoside diphosphates and triphosphates.
Douglas Jardim-Messeder +4 more
doaj +2 more sources
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing ...
Dennis J, Cada, Danial E, Baker
openaire +2 more sources
Inhibitors of the Cancer Target Ribonucleotide Reductase, Past and Present
Ribonucleotide reductase (RR) is an essential multi-subunit enzyme found in all living organisms; it catalyzes the rate-limiting step in dNTP synthesis, namely, the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates.
Sarah E. Huff +2 more
doaj +1 more source
Vγ9Vδ2 T cells is the dominant γδ T cell subset in human blood. They are cytotoxic and activated by phosphoantigens whose concentrations are increased in cancer cells, making the cancer cells targets for Vγ9Vδ2 T cell immunotherapy.
Chenxiao Liu +3 more
doaj +1 more source
URIDINE DIPHOSPHATE ACETYLGLUCOSAMINE
Blanco y ...
Cabib, Enrico +2 more
openaire +6 more sources

