Characterization of enzyme activities and cofactors involved in bioactivation and bioinactivation of chemical carcinogens in the tester strains Escherichia coli K12 MX100 and Salmonella typhimurium LT2 TA100. [PDF]
MX100 is an Escherichia coli K12 genotoxicity tester strain, especially developed for mechanistic studies of chemical mutagens and carcinogens. For the study of the role of specific enzymes in the bioactivation and bioinactivation of carcinogens, it is ...
Rueff, J. +5 more
core +1 more source
Objective: Thimerosal is an important preservative in vaccines and ophthalmologic preparations. The substance is known to be a type IV sensitizing agent.
Bauer, A. +10 more
core +1 more source
Metabolic problems lead to numerous failures during clinical trials, and much effort is now devoted in developing in silico models predicting metabolic stability and metabolites.
G. Vistoli +7 more
core +1 more source
Biocatalytic organofluorine synthesis via hemoprotein-catalyzed carbene transfer reactions
Thesis (Ph. D.)--University of Rochester. Department of Chemistry, 2020.Protein engineering efforts in our laboratory led to the development of efficient hemoprotein-based biocatalysts for abiological carbene transfer reactions.
Fasan, Rudi, Tinoco Valencia, Antonio
core
Amide and Thioester Synthesis Via Oxidative Coupling of Alcohols with Amines or Thiols Using Alcohol Dehydrogenases. [PDF]
Damian M +4 more
europepmc +1 more source
Alkyltransferase Ribozyme for Site-Specific N<sup>4</sup>-Cytidine Alkylation. [PDF]
Dorinova E, Walunj MB, Höbartner C.
europepmc +1 more source
Basic importance: mechanistic molecular modeling of the <i>ent</i>-copalyl diphosphate synthase from <i>Arabidopsis thaliana</i> (AtCPS). [PDF]
Torrence IS +3 more
europepmc +1 more source
Designed Water Capture in Terpene Synthase Catalysis. [PDF]
Srivastava PL, Miller DJ, Allemann RK.
europepmc +1 more source
Peeking behind the carbocation: identification of (alternative) catalytic bases in the class II active site of conifer resin acid diterpene synthases. [PDF]
Raslan AMAA, Peters RJ.
europepmc +1 more source
Merging Biocatalysis and Chemocatalysis in Flow: State-of-the-Art and Future Directions for Sustainable Synthesis. [PDF]
Siasiaridis P, Damian M, Mutti FG.
europepmc +1 more source

