Results 21 to 30 of about 1,982 (88)

Origin and characterization of cyclodepsipeptides: Comprehensive structural approaches with focus on mass spectrometry analysis of alkali‐cationized molecular species

Mass Spectrometry Reviews, Volume 44, Issue 6, Page 1013-1098, November/December 2025.
Abstract Cyclodepsipeptides (CDPs) represent a huge family of chemically and structurally diverse molecules with a wide ability for molecular interactions. CDPs are cyclic peptide‐related natural products made up of both proteinogenic and nonproteinogenic amino acids linked by amide and ester bonds.
Sophie Liuu, Annelaure Damont, Alain Perret, Olivier Firmesse, François Becher, Gwenaëlle Lavison‐Bompard, Amandine Hueber, Amina S. Woods, Ekaterina Darii, François Fenaille, Jean‐Claude Tabet   +10 more
wiley   +1 more source

Engineering Alloxazines by Boron Coordination and Click Chemistry toward Small‐molecule Fluorescent Probes

Chemistry – A European Journal, Volume 31, Issue 47, August 21, 2025.
The design of fluorescent molecules inspired by natural cofactors to monitor biological processes carries some intrinsic advantages. This is particularly relevant in the case of redox cofactors with innate fluorescence properties, such as flavins, and synthetic strategies toward their functionalized analogues are of high interest to modulate properties.
Oscar Charpentier, Ambroise Mouhanna, Eleanna Nikolopoulos, Aurélie Guenet, Christophe Gourlaouen, Marine Desage‐El Murr   +5 more
wiley   +1 more source

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, Volume 64, Issue 27, July 1, 2025.
Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T. Bornscheuer   +4 more
wiley   +1 more source

Piperazine Derivatives Attenuate Scopolamine‐Induced Memory Deficits by Modulating Neuroinflammation and Oxidative Stress via the NF‐κB/TNF‐α/COX‐2 Pathway

ChemistrySelect, Volume 10, Issue 25, July 4, 2025.
Piperazine derivatives 2b, 2f, and 2h reduce neuroinflammation, oxidative stress, and memory impairment by modulating COX‐2, p‐NF‐κB, and TNF‐α pathways, showing promise as lead compounds for neurodegenerative disease drug development. Abstract Oxidative stress‐induced neuro‐inflammatory events are common in neurodegenerative illnesses, addressing ...
Sadaf Fardoos, Sidra Kaleem, Syed Muzzammil Masaud, Faryal Jahan, Humaira Nadeem, Muhammad Afzal, Abdulwahed Fahad Alrefaei, Eman Alshehri, Sajid Ali   +8 more
wiley   +1 more source

Over-expression, purification, and kinetic analysis of <i>Mycobacterium tuberculosis</i> WecA. [PDF]

J Enzyme Inhib Med Chem
Zhao Y, Jia H, Wang Y, Sha S, An D, Yang S, Qian L, Ma Y, Xu L.   +8 more
europepmc   +1 more source

Stereospecific Enzymatic Conversion of Boronic Acids to Amines. [PDF]

J Am Chem Soc
Hanley D, Li ZQ, Gao S, Virgil SC, Arnold FH, Alfonzo E.   +5 more
europepmc   +1 more source

Strong Implications From Small Deviations in Labeling Patterns: The Mechanism of Burkholderia gladioli Pacifigorgiadiene Synthase. [PDF]

Chemistry
Yin Z, Hu Z, He X, Xu J, Goldfuss B, Dickschat JS, Bian G.   +6 more
europepmc   +1 more source

Biocatalytic Synthesis of α-Amino Esters via Nitrene C-H Insertion. [PDF]

J Am Chem Soc
Alfonzo E, Hanley D, Li ZQ, Sicinski KM, Gao S, Arnold FH.   +5 more
europepmc   +1 more source

Metabolic Stability of Fluorinated Small Molecules: A Physical Organic Chemistry Perspective. [PDF]

J Med Chem
Bhattarai P, Trombley TA, Altman RA.
europepmc   +1 more source

Docking in the Abies grandis abietaenol synthase to investigate the mechanism underlying conifer resin acid diterpene synthase evolution. [PDF]

Biochem J
Schmidt-Dannert M, Humphreys G, Eich T, Jia M, Peters RJ.   +4 more
europepmc   +1 more source