Results 41 to 50 of about 3,627 (132)
Deprotective Functionalization: An Emerging Concept for Amine Reactivity
Chemistry – A European Journal, Volume 32, Issue 4, 23 January 2026.While protecting groups are indispensable in total synthesis to avoid undesired reactivity, installation and removal of protecting groups lead to an increase in the step‐count, cost, waste production and time requirement. One approach tackling these drawbacks is deprotective functionalization, which combines deprotection and postfunctionalization in a ...
Irmgard Tiefenbrunner +2 more
wiley +1 more source
Irreversible inhibitors and activity-based probes as research tools in chemical glycobiology [PDF]
, 2011 In this review, we will discuss the enzymes that are involved in the synthesis and degradation of glycoconjugates and we will give an overview of the inhibitors and activity-based probes (ABPs) that have been used to study these.
Aerts, Johannes M.F.G. +3 more
core +2 more sources
Microbial β-Glucosidase: sources, production and applications [PDF]
, 2017 Cellulose is the most abundant biopolymer in biosphere and the major constituent of plant biomass. Cellulose polymer is made up of β-glucose units linked by β-glucosidic bonds. Cellulase is an enzymatic system that catalyzes the hydrolysis of cellulose
Ahmed, Amer +3 more
core
approach to screen compounds active against parasitic nematodes of major socio-economic importance [PDF]
, 2011 Infections due to parasitic nematodes are common causes of morbidity and fatality around the world especially in developing nations. At present however, there are only three major classes of drugs for treating human nematode infections.
Varun Khanna, Shoba Ranganathan
core +1 more source
Advanced Science, Volume 13, Issue 6, 30 January 2026.A luciferase is used as biosensor for aldehydes, produced enzymatically from different monomeric building blocks of plastics like polyurethanes (PUs). The screening platform is used to monitor esterase, amidase, and urethanase activity and to guide the selection of enzyme variants with improved hydrolytic activities toward difficult to hydrolyze ...
Ina Somvilla +12 more
wiley +1 more source
Fragment-based approaches to TB drugs. [PDF]
, 2018 Tuberculosis is an infectious disease associated with significant mortality and morbidity worldwide, particularly in developing countries. The rise of antibiotic resistance in Mycobacterium tuberculosis (Mtb) urgently demands the development of new drug ...
Abell, Chris +3 more
core +1 more source
Advanced Science, Volume 12, Issue 45, December 4, 2025.Ischemic stroke is a serious disease with high rates of mortality and disability, but there is a lack of novel therapeutic targets and agents for it. Now it is shown that Ras GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1) has the potential to serve as a therapeutic target for ischemic stroke.
Heyanhao Zhang +10 more
wiley +1 more source
An investigation of Ru(II) complexes containing sterically demanding imido ligands : a thesis presented to Massey University in partial fulfilment of the requirements for the degree of Master of Science [PDF]
, 1995 Monomeric, low oxidation state, ruthenium imido compounds, (η6 -arene) RuN-Ar' (arene= p-cymene and C6 Me6 ; Ar'= 2,4,6-tri-tert-butylphenyl) have been synthesized from [(η6 -arene) RuCl2 ]2 and 4 equiv of LiNHAr' in THF.
Steedman, Andrew John
core
, 2010 The insecticide synergist, piperonyl butoxide (PBO), has been used to reduce resistance factors and to characterise metabolic resistance resulting from mixed function oxidases (MFOs).
Philippou, Despina, Philippou, Despina
core +1 more source
Opportunities When Chemistry Meets Biology in Catalysis and Synthesis
Transformative Chemistry, Volume 1, Issue 1, December 2025.Biosynthesis and chemical synthesis possess complementary strengths and limitations. Integrating these two systems across multiple levels offers opportunities for molecular synthesis to become highly efficient, precise, versatile, and scalable in the future, while also ensuring environmental compatibility and resource renewability.
Xiao Xiao +5 more
wiley +1 more source