Results 51 to 60 of about 3,627 (132)

Cobalamin‐Dependent Aryl Methyl Ether O‐Demethylases: Promising Enzymes for Biocatalytic Applications from Lignin Valorization to Organic Synthesis

ChemCatChem, Volume 17, Issue 21, November 10, 2025.
Cobalamin‐dependent aryl methyl ether O‐demethylases have high potential for biocatalytic applications, including lignin valorization and synthetic chemistry. In this review, we provide a detailed overview of such O‐demethylase systems identified to date from various microorganisms, including their mechanism, substrate scope and selectivity, and ...
Niels Krabbe Johnsen, Santipap Chaiyasarn, Zheng Guo, Jaehong Han, Bekir Engin Eser   +4 more
wiley   +1 more source

Origin and characterization of cyclodepsipeptides: Comprehensive structural approaches with focus on mass spectrometry analysis of alkali‐cationized molecular species

Mass Spectrometry Reviews, Volume 44, Issue 6, Page 1013-1098, November/December 2025.
Abstract Cyclodepsipeptides (CDPs) represent a huge family of chemically and structurally diverse molecules with a wide ability for molecular interactions. CDPs are cyclic peptide‐related natural products made up of both proteinogenic and nonproteinogenic amino acids linked by amide and ester bonds.
Sophie Liuu, Annelaure Damont, Alain Perret, Olivier Firmesse, François Becher, Gwenaëlle Lavison‐Bompard, Amandine Hueber, Amina S. Woods, Ekaterina Darii, François Fenaille, Jean‐Claude Tabet   +10 more
wiley   +1 more source

EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF); Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 [PDF]

, 2011
<p>The CEF Panel of the European Food Safety Authority was requested to evaluate 80 flavouring substances in the Flavouring Group Evaluation 08, Revision 4, using the Procedure in Commission Regulation (EC) No 1565/2000.
Aeschbacher, Ames, Atochem, Atochem, Auletta, Bailey, Bailey, Bailey, Ballantyne, Black, Brams, Bremer, Brigelius, Brown, Butterworth, Butterworth, Canellakis, Cashman, Cashman, Cashman, Cashman, Chatterji, CoE, Collinson, Cotgreave, Cox, Cox, Cox, Cox, Cox, Cramer, Damani, Degroot, Deslongchamps, Dooley, Dorange, Dutton, EC, EC, EC, EC, EC, Eder, Eder, Edsbacker, EFFA, Elfarra, Fairchild, Feng, Fenwick, Finkelstein, Fishman, Fogleman, Fogleman, Fogleman, Gachon, Gallo, George, Greenzaid, Griffiths, Grosa, Gry, Hakura, Hermansky, Hitchcock, Holloway, Hoodi, Hosono, Hucker, IOFI, Ito, JECFA, JECFA, Karim El Fatih, Keith, Koptyaev, Kurooka, LaVoie, Layman, Lee, Levine, Maiorino, Marks, Marks, Mazel, McBain, Min, Mitchell, Mondino, Mondino, Mondino, Mondino, Moran, Moreno, Morgareidge, Morgareidge, Morgareidge, Morgareidge, Morgareidge, Munday, Munday, Munday, Musk, Myers, Münchberg, Nakamura, Nakamura, Nakamura, Nickson, Nickson, Nnane, Noel, Oae, Oginsky, Onkenhout, Oser, Oser, Pacifici, Panasevich, Peano, Pence, Piccirillo, Posternak, Renwick, Renwick, Renwick, Renwick, Rettie, Rettie, Richardson, Rosen, Rosen, Sadeque, Sadeque, Satchell, Schafer, Shaw, Sheen, Shellenberger, Shellenberger, Sies, Snow GA, Sommer, Steele, Steele, Stien, Strong, Strong, Szumlanski, Takata, Tamaki, Tateishi, Taylor, Thomas, Thurston, TNO, TNO, Ubuka, Vogin, Waring, Watanabe, Watanabe, Watanabe, Watanabe, Wheldon, Wild, Williams, Williams, Willson, Wnorowski, Wnorowski, Wnorowski, Wnorowski, Wnorowski, Wnorowski, Wood, Woodson, Woodson, Woodson, Yashiro, Yoshihara, Zeiger, Ziegle, Ziegler, Ziegler, Ziegler   +185 more
core   +6 more sources

Targeting antibiotic resistance [PDF]

, 2016
Finding strategies against the development of antibiotic resistance is a major global challenge for the life sciences community and for public health.
Chellat, Mathieu F., Raguž, Luka, Riedl, Rainer   +2 more
core   +1 more source

Fungal cyclooligomer depsipeptides: From classical biochemistry to combinatorial biosynthesis [PDF]

, 2011
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence
Döhren, Hans von, Molnár, István, Müller, Jane, Süßmuth, Roderich D.   +3 more
core   +2 more sources

Engineering Alloxazines by Boron Coordination and Click Chemistry toward Small‐molecule Fluorescent Probes

Chemistry – A European Journal, Volume 31, Issue 47, August 21, 2025.
The design of fluorescent molecules inspired by natural cofactors to monitor biological processes carries some intrinsic advantages. This is particularly relevant in the case of redox cofactors with innate fluorescence properties, such as flavins, and synthetic strategies toward their functionalized analogues are of high interest to modulate properties.
Oscar Charpentier, Ambroise Mouhanna, Eleanna Nikolopoulos, Aurélie Guenet, Christophe Gourlaouen, Marine Desage‐El Murr   +5 more
wiley   +1 more source

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, Volume 64, Issue 27, July 1, 2025.
Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T. Bornscheuer   +4 more
wiley   +1 more source

Piperazine Derivatives Attenuate Scopolamine‐Induced Memory Deficits by Modulating Neuroinflammation and Oxidative Stress via the NF‐κB/TNF‐α/COX‐2 Pathway

ChemistrySelect, Volume 10, Issue 25, July 4, 2025.
Piperazine derivatives 2b, 2f, and 2h reduce neuroinflammation, oxidative stress, and memory impairment by modulating COX‐2, p‐NF‐κB, and TNF‐α pathways, showing promise as lead compounds for neurodegenerative disease drug development. Abstract Oxidative stress‐induced neuro‐inflammatory events are common in neurodegenerative illnesses, addressing ...
Sadaf Fardoos, Sidra Kaleem, Syed Muzzammil Masaud, Faryal Jahan, Humaira Nadeem, Muhammad Afzal, Abdulwahed Fahad Alrefaei, Eman Alshehri, Sajid Ali   +8 more
wiley   +1 more source

La click-chemistry en el descubrimiento de fármacos [PDF]

, 2016
La revisión bibliográfica que se presenta a continuación trata sobre la llamada clickchemistry y su aplicación en el descubrimiento de fármacos. Para ello se parte de la definición de click-chemistry y sus principales características que la hacen ...
González Vázquez, María
core  

Selectivity on-target of bromodomain chemical probes by structure-guided medicinal chemistry and chemical biology [PDF]

, 2016
Targeting epigenetic proteins is a rapidly growing area for medicinal chemistry and drug discovery. Recent years have seen an explosion of interest in developing small molecules binding to bromodomains, the readers of acetyl-lysine modifications.
Alessio Ciulli, Carles Galdeano, Chiang C-M, Lejeune P   +3 more
core   +2 more sources