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Calcium pyrophosphate dihydrate crystal deposition disease
Current Problems in Diagnostic Radiology, 1982Abstract CPPD crystal deposition disease is a general term for a disorder characterized by the presence of CPPD crystals in or around joints. Clinical presentations of this disease are widely varied, and radiologic features can be very suggestive if not diagnostic of its presence.
C S, Resnik, D, Resnick
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Calcium Pyrophosphate Dihydrate Crystal Deposition Disease
Archives of Internal Medicine, 1969Eighteen patients had definite calcium pyrophosphate dihydrate crystal deposition disease (pseudogout) as shown by clinical and roentgenographic findings plus results of synovial fluid analyses. Seventy-two percent of the patients had diabetes mellitus and 33% had hypertension.
M, Skinner, A S, Cohen
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Management of calcium pyrophosphate crystal deposition disease: A systematic review
Seminars in Arthritis and Rheumatism, 2021Calcium pyrophosphate crystal deposition disease (CPPD) is a common cause of acute and chronic arthritis, especially in the elderly population. There is a paucity of data regarding the management of CPPD disease, which is currently based on expert opinion and evidence derived from the treatment of gout.
Konstantinos, Parperis +3 more
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Diseases associated with calcium pyrophosphate dihydrate crystal deposition
The American Journal of Medicine, 1974Abstract A comparison of the frequency of hypertension, diabetes mellitus, urate gout, hemochromatosis, azotemia and hyperparathyroidism in 28 pseudogout patients and 22 control subjects with osteoarthritis of the large weight-bearing joints failed to provide statistical evidence of intergroup differences.
D J, McCarty +6 more
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Calcium pyrophosphate crystal deposition disease and other crystal deposition diseases
Current Opinion in Rheumatology, 1995A number of cells, chemotactic factors, and inflammatory mediators are implicated in the complex mechanisms underlying crystal-mediated inflammation. Interleukin-8, released from mononuclear cells that have been exposed to urate and other crystals, is a potent chemotaxin and activator of neutrophils.
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Pathogenesis of calcium pyrophosphate crystal deposition disease
Current Rheumatology Reports, 2001Calcium pyrophosphate dihydrate deposition (CPPDD) disease is an increasingly common form of arthritis affecting the elderly. It is characterized by the formation of CPPD crystals in articular cartilage and usually results in severe cartilage destruction with loss of joint function. This article discusses our understanding of how and why these crystals
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Calcium pyrophosphate dihydrate crystal deposition and other crystal deposition diseases
Current Opinion in Rheumatology, 1994Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease continues to be of intense clinical and basic science interest. Follow-up of studies of hereditary CPPD crystal deposition indicate differences from the common sporadic disease. The results of a prospective study of CPPD crystal deposition arthropathy confirm that clinical symptoms ...
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Calcium pyrophosphate dihydrate crystal deposition and other crystal deposition diseases
Current Opinion in Rheumatology, 1993Recent advances in understanding the pathogenesis and mechanisms of tissue damage related to calcium-containing crystals are highlighted in this review. The clinical spectrum of diseases related to crystal deposition has broadened and includes distinct neurologic syndromes associated with hypertrophy and calcification of the ligamentum flavum or ...
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Arthritis & Rheumatism, 1991
Inorganic pyrophosphate (PPi) levels were estimated by radiometric assay in urine and in synovial fluid (SF) from asymptomatic, nonarthritic knees of patients with untreated metabolic disease and normal controls. SF PPi was significantly elevated in patients with hyperparathyroidism (mean +/- SEM 19 +/- 3 microM; n = 9), hemochromatosis (23 +/- 5 ...
M, Doherty +3 more
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Inorganic pyrophosphate (PPi) levels were estimated by radiometric assay in urine and in synovial fluid (SF) from asymptomatic, nonarthritic knees of patients with untreated metabolic disease and normal controls. SF PPi was significantly elevated in patients with hyperparathyroidism (mean +/- SEM 19 +/- 3 microM; n = 9), hemochromatosis (23 +/- 5 ...
M, Doherty +3 more
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An update on the epidemiology of calcium pyrophosphate dihydrate crystal deposition disease
Rheumatology, 2009The aim of this review is to summarize recent research relating to the epidemiology of chondrocalcinosis (CC), including prevalence of CC, the association between CC and OA, familial forms of CC and diseases associated with CC. We searched MEDLINE for articles published in English from 1998 to 2008 using MEsH terms covering all aspects of the ...
Pascal, Richette +2 more
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