Results 181 to 190 of about 5,707,552 (346)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Comment on: "Comparison of automatic versus constant CPAP in elderly patients after major abdominal surgery: a randomized noninferiority trial". [PDF]

Braz J Anesthesiol
Sethuraman RM, Theagrajan A, Babu A.
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Evaluation of 7 modern IOL power calculation formulas in two PARTIAL-Range of Field IOL designs and a new constant optimization method. [PDF]

BMC Ophthalmol
Zhu M, Zeng Z, Zhang Z, Zhang G.
europepmc   +1 more source

Calculation of traction force of a cylindrical linear brushless engine for driving a plunger pump

, 2019
Vladislav Shaposhnikov, Roman Tokarev, Aleksandr Korotaev, Е. А. Чабанов   +3 more
openalex   +1 more source

Efficient and private approximations of distributed databases calculations [PDF]

, 2017
Philip Derbeko, Shlomi Dolev, Ehud Gudes, Jeffrey D. Ullman   +3 more
openalex   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

An Enhanced Event-Based Model for Integrated Flight Safety of Fixed-Wing UAVs. [PDF]

Sensors (Basel)
Ma X, Lu X, Li H, Lu X, Li J, Zhao J.
europepmc   +1 more source

First-principles calculations of structural and electronic properties of SrSi2 under pressure.

, 2014
Iosr Journals, Md. Atikur Rahman
openalex   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source