Results 211 to 220 of about 5,707,552 (346)
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
A Tutorial on Sample Size Calculation for Inter-rater and Intra-rater Agreement Studies. [PDF]
Madadizadeh F, Bahariniya S.
europepmc +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Reliability analysis of horseshoe tunnels by radial-based importance sampling method based on complex function displacement solution. [PDF]
Rong Y +5 more
europepmc +1 more source
On the calculation of low-frequency oscillations of the Earth's core [PDF]
Sergei Diakonov
openalex +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Multi-objective optimization design of oil spray cooling system for hairpin motor based on particle swarm optimization-backpropagation-non-dominated sorting genetic algorithm III. [PDF]
Liu Y +5 more
europepmc +1 more source

