Results 41 to 50 of about 214,662 (263)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
CALCULATION AND OPTIMIZATION OF DIE FORGING PROCESSES
The review of methods of calculation and optimization of die forging processes is submitted. The scheme of direct and inverse mathematical simulation of metal forming and methods realization of calculation are considered.
Yu.N. REZNIKOV, A.V. VOVCHENKO
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
CALCULATION AND OPTIMIZATION OF DIE FORGING PROCESSES
The review of methods of calculation and optimization of die forging processes is submitted. The scheme of direct and inverse mathematical simulation of metal forming and methods realization of calculation are considered.
Yu.N. REZNIKOV, A.V. VOVCHENKO
doaj
An example of goal-directed, calculational proof
Abstract An equivalence relation can be constructed from a given (homogeneous, binary) relation in two steps: first, construct the smallest reflexive and transitive relation containing the given relation (the “star” of the relation) and, second, construct the largest symmetric relation that is included in the ...
ROLAND CARL BACKHOUSE +2 more
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
DETERMINATION OF PARASITE DRAG FOR COMMERCIAL AIRPLANE AT TRANSONIC SPEEDS
It considers the task of determination of parasite drag for subsonic commercial airplane on the base of theoretical calculation procedures. It contains the procedure for clarification of empirical approach to calculation of parasite drag at high speeds ...
V. I. Shevyakov
doaj
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source

