Results 71 to 80 of about 1,445,100 (299)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Comparison Between HB and ISO Standard for Calculating Bevel Gear Tooth Surface Contact Fatigue Strength

Jixie chuandong, 2021
In order to correctly evaluate the gear strength calculation results in different standards， the difference between Chinese aviation industry standard （HB） and international standardization organization standard （ISO） in calculating the load capacity of ...
Wenshuang Teng, Mei Guo, Zhenhai Song
doaj  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Reliability Calculation of Mechanical Transmission System with Correlative Failure Among Components

Jixie chuandong, 1994
This paper discusses reliability calculation of mechanical transmission system with correlative failure among components,points out the deficiency in present model for reliability calculation of mechanical transmission system,and introduces a general ...
Du Xiaoping
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

AtomSim: web-deployed atomistic dynamics simulator [PDF]

, 2010
AtomSim, a collection of interfaces for computational crystallography simulations, has been developed. It uses forcefield-based dynamics through physics engines such as the General Utility Lattice Program, and can be integrated into larger computational ...
Fennick, Jacob R., Fultz, Brent, Junkermeier, Chad E., Keith, J. Brandon, Lewis, James P., Li, Chen W., Lin, Jiao Y. Y., McKerns, Michael M., Nelson, Daniel R.   +8 more
core  

The $\hat{\Gamma}$-genus and a regularization of an $S^1$-equivariant Euler class

, 2008
We show that a new multiplicative genus, in the sense of Hirzebruch, can be obtained by generalizing a calculation due to Atiyah and Witten. We introduce this as the $\hat{\Gamma}$-genus, compute its value for some examples and highlight some of its ...
Atiyah M F, Barth W, Berline N, Cartan H, Cartan H, Cartier P, Cohen R L, Guillemin V W, Hirzebruch F, Katzarkov L Kontsevich M Pantev T, Libgober A S, Libgober A S, Macdonald I G, McLaughlin D A, Rongmin Lu, Segal G, Witten E   +16 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Calculation method and evaluation of surrounding rock pressure of vertical shaft

Scientific Reports
The surrounding rock pressure of vertical shafts is one of the basic parameters of shaft lining design. Investigating its calculation methods and applicable scopes has great engineering significance.
Zhongxi Tian, Yuanwu Sun, Qingshuang Zhao, Boliang Zhang, Wanrong Liu, Xutao Zhang   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source