Results 71 to 80 of about 1,447,843 (300)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Comparison Between HB and ISO Standard for Calculating Bevel Gear Tooth Surface Contact Fatigue Strength

Jixie chuandong, 2021
In order to correctly evaluate the gear strength calculation results in different standards， the difference between Chinese aviation industry standard （HB） and international standardization organization standard （ISO） in calculating the load capacity of ...
Wenshuang Teng, Mei Guo, Zhenhai Song
doaj  

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Reliability Calculation of Mechanical Transmission System with Correlative Failure Among Components

Jixie chuandong, 1994
This paper discusses reliability calculation of mechanical transmission system with correlative failure among components,points out the deficiency in present model for reliability calculation of mechanical transmission system,and introduces a general ...
Du Xiaoping
doaj  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Calculation method and evaluation of surrounding rock pressure of vertical shaft

Scientific Reports
The surrounding rock pressure of vertical shafts is one of the basic parameters of shaft lining design. Investigating its calculation methods and applicable scopes has great engineering significance.
Zhongxi Tian, Yuanwu Sun, Qingshuang Zhao, Boliang Zhang, Wanrong Liu, Xutao Zhang   +5 more
doaj   +1 more source

The bridge between design and analysis

Perspectives on Medical Education, 2017
The overall purpose of the ‘Statistical Points and Pitfalls’ series is to help readers and researchers alike increase awareness of how to use statistics and why/how we fall into inappropriate choices or interpretations. We hope to help readers understand
Jimmie Leppink, Patricia O’Sullivan, Kal Winston   +2 more
doaj   +1 more source

Resonance Lifetimes from Complex Densities

, 2009
The ab-initio calculation of resonance lifetimes of metastable anions challenges modern quantum-chemical methods. The exact lifetime of the lowest-energy resonance is encoded into a complex "density" that can be obtained via complex-coordinate scaling ...
Aguilar J., Balslev E., Buchleitner A., Chu S., Deych L. I., Donnelly R. A., Doolen G. D., Ernzerhof M., Hein S., Ho Y. K., Hohenberg P., Honigmann M., Junker B. R., Kohn W., Krueger A. J., Marston C. C., McCurdy C. W., Moiseyev N., Moiseyev N., Moiseyev N., Nesbet R. K., Nielsen E. S., Nordlander P., Nordlander P., Nordlander P., Palmer R. E., Puiatti M., Reinhardt W. P., Rienstra-Kiracofe J. C., Runge E., Simon B., Simons J., Taylor J. R., Telnov D. A., von Weizsacker C. F., Wasserman A.   +35 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source