Results 91 to 100 of about 49,947 (296)
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
ON THE REMOVAL OF ENORMOUS VESICAL CALCULI BY THE SUPRA-PUBIC ROUTE WITH REPORT OF A RECENT SUCCESSFUL CASE [PDF]
, 1890 J. WILLIAM WHITE
openalex +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
An Intrauterine Contraceptive Device that Migrated to the Bladder and Encrusted
İstanbul Medical Journal, 2017 Intrauterine contraceptive devices (IUDs) are frequently used for birth control. Side-effects such as vaginal bleeding and localized pelvic pain are most common, and uterine perforation and migration of the adjacent organs are rare, but serious ...
Mehmet Gökhan Çulha +4 more
doaj +1 more source
The X-Ray Diagnosis of Renal and Ureteral Calculi [PDF]
, 1908 G. Harrison Orton
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Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
The Increased Risk of Renal Stones in Patients With COVID-19 Infection
Pharmaceutical and Biomedical Research, 2022 Background: The novel coronavirus disease (caused by SARS-CoV-2) has become a disaster all over the world. Based on available evidence, the main organ infected by this virus is the respiratory system; however, various other vital systems can also be ...
Hossein Kasiri +3 more
doaj
A Case of Intra-Vesical Cyst of the Ureter: Dilatation of Ureter with Very Slight Dilatation of the Renal Pelvis and Containing Twenty-Eight Movable Calculi; Bacteriuria; Alkalinuria; Phosphaturia [PDF]
, 1908 E. A. CODMAN
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Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source