Results 61 to 70 of about 94,010 (359)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Clinical features analysis of inflammatory myofibroblastic tumors of the retroperitoneal and genitourinary system

BMC Urology
Objective To explore the clinical features of inflammatory myofibroblastic tumors (IMT) of the retroperitoneal and genitourinary system. Methods We conducted a retrospective analysis of the clinical data of 23 patients with pathologically confirmed ...
Qianhao Huang, Meixuan Ding, Yifan Huang, Xin Lian, Yijie Xie, Tao Wang, Bin Chen, Yuedong Chen   +7 more
doaj   +1 more source

Efficacy and safety of Ho:YAG Laser Lithotripsy for ureteroscopic removal of proximal and distal ureteral calculi

BMC Urology, 2014
BackgroundLaser lithotripsy is an established endourological modality. Ho:YAG laser have broadened the indications for ureteroscopic stone managements to include larger stone sizes throughout the whole upper urinary tract.
W. Khoder, M. Bader, R. Sroka, C. Stief, R. Waidelich   +4 more
semanticscholar   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Methuosis Inducer SGI‐1027 Cooperates with Everolimus to Promote Apoptosis and Pyroptosis by Triggering Lysosomal Membrane Permeability in Renal Cancer

Advanced Science
The mTOR inhibitor everolimus has been approved as a sequential or second‐line therapy for renal cell carcinoma (RCC). However, the development of drug resistance limits its clinical applications.
Yu Luo, Bing Guan, Xiaoqi Deng, Peide Bai, Haichao Huang, Chaohao Miao, Anran Sun, Zhipeng Li, Dianqiang Yang, Xuegang Wang, Zhiqiang Shao, Yulong Wu, Jinchun Xing, Bin Chen, Tao Wang   +14 more
doaj   +1 more source

MP29-11 NEPHROSTOMY TUBE VS. URETERAL STENT FOR OBSTRUCTING SEPTIC CALCULI: A NATIONWIDE PROPENSITY SCORE MATCHED ANALYSIS [PDF]

, 2021
Rachel Wong, Sylvain Lother, Premal A. Patel, Barret Rush   +3 more
openalex   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Gallstone ileus with a biliodigestive fistula

Journal of the Belgian Society of Radiology, 2013
Background: A 34-year-old woman with breast cancer, metastasized to bone and brain, was admitted to our hospital with abdominal discomfort, nausea and constipation. Physical examination revealed a diffuse tender abdomen without bowel sounds.
LJ Schijf, D Van der Vlies, AG Aalbers, A Bruining   +3 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

A vesicocutaneous fistula secondary to bladder calculi in a patient with spina bifida

Journal of Surgical Case Reports, 2010
We present a rare case of a vesicocutaneous fistula secondary to two large bladder calculi in a patient with spina bifida. A 62 year old lady presented with swelling of her right thigh and a calcified mass protruding through the subcutaneous tissues of ...
Jonathan D Horsnell, Richard B Kinder
doaj