Results 161 to 170 of about 76,910 (285)

When Hydronephrosis Was Not Physiological: A Case of Septic Shock Secondary to Obstructive Uropathy in Pregnancy. [PDF]

Cureus
Chowdhury S, Amoo WA, Surendran S, Pilkington L.   +3 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Urologically silent intravesical migration of a copper intrauterine device presenting as chronic pelvic pain: CT features and comparison with reported cases. [PDF]

Radiol Case Rep
Hafsi M, Zouaghi A, Yaich O, Hafsi A, Azzouzi S, Jellali N.   +5 more
europepmc   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

En bloc removal of a giant renal calculus in a single sitting via transperitoneal laparoscopic pyelolithotomy: a safe and effective minimally invasive alternative. [PDF]

J Surg Case Rep
Pipal DK, Gupta G, Prasad S, Rajesh Kannan L, Philips A, Nikhil B, Sai S, Aaqib RM, Prasad V, Yadav P, Mishra D, Srivastav T, Murgod NB.   +12 more
europepmc   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Palaeoproteomic and genetic insights into millennial-scale dairy consumption in Armenia. [PDF]

iScience
Antonosyan M, Hovhannisyan A, Roberts P, Cassidy LM, Mkrtchyan S, Simonyan H, Bobokhyan A, Aghikyan L, Piliposyan A, Badalyan R, Yeranyan N, Gnuni A, Avetisyan H, Badalyan M, Gabrielyan A, Sarkisian N, Grigoryan A, Simonyan H, Safaryan M, Vardanyan B, Martirosyan-Olshansky K, Jackson I, Breslin E, Gyonjyan A, Khachatryan Z, Ilgner J, Yepiskoposyan L, Manica A, Bradley DG, Boivin N, Wilkin S.   +30 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Retrograde intrarenal surgery in a non-fused left crossed ectopic kidney with large renal calculus: a case report and review of literature. [PDF]

Oxf Med Case Reports
Anwaar A, Haq IU, Khan AM, Hameed F, Akilimali A.   +4 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source