Results 121 to 130 of about 47,126 (303)

Auxiliary Diagnosis of Dental Calculus Based on Deep Learning and Image Enhancement by Bitewing Radiographs

Bioengineering
In the field of dentistry, the presence of dental calculus is a commonly encountered issue. If not addressed promptly, it has the potential to lead to gum inflammation and eventual tooth loss.
Tai-Jung Lin, Yen-Ting Lin, Yuan-Jin Lin, Ai-Yun Tseng, Chien-Yu Lin, Li-Ting Lo, Tsung-Yi Chen, Shih-Lun Chen, Chiung-An Chen, Kuo-Chen Li, Patricia Angela R. Abu   +10 more
doaj   +1 more source

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

Advanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang   +16 more
wiley   +1 more source

Hierarchical Summary Statistics Encoding Across Primary Visual and Posterior Parietal Cortices

Advanced Science, EarlyView.
This study shows that mouse V1 simultaneously encodes the ensemble mean and variance of motion, providing a robust summary‐statistic representation that persists despite single‐neuron variability. These signals propagate to PPC, where they are transformed into abstract category representations during decision making.
Young‐Beom Lee, Oliver James, Gaeun Jung, Doyun Lee, Yee‐Joon Kim   +4 more
wiley   +1 more source

MAPPNet: A Multi-Scale Attention Pyramid Pooling Network for Dental Calculus Segmentation

Applied Sciences
Dental diseases are among the most prevalent diseases globally, and accurate segmentation of dental calculus images plays a crucial role in periodontal disease diagnosis and treatment planning.
Tianyu Nie, Shihong Yao, Di Wang, Conger Wang, Yishi Zhao   +4 more
doaj   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

Exploring the potential of dental calculus to shed light on past human migrations in Oceania

Nature Communications
The Pacific islands and Island Southeast Asia have experienced multiple waves of human migrations, providing a case study for exploring the potential of ancient microbiomes to study human migration. We perform a metagenomic study of archaeological dental
Irina M. Velsko, Zandra Fagernäs, Monica Tromp, Stuart Bedford, Hallie R. Buckley, Geoffrey Clark, John Dudgeon, James Flexner, Jean-Christophe Galipaud, Rebecca Kinaston, Cecil M. Lewis, Elizabeth Matisoo-Smith, Kathrin Nägele, Andrew T. Ozga, Cosimo Posth, Adam B. Rohrlach, Richard Shing, Truman Simanjuntak, Matthew Spriggs, Anatauarii Tamarii, Frédérique Valentin, Edson Willie, Christina Warinner   +22 more
doaj   +1 more source

Fusobacterium Nucleatum Dna In Dental Calculus From Ancient Siberian Populations

International Dental Journal
Aim or purpose: To assess the possibility of DNA preservation of periodontopathogenic microorganisms in the archaeological material of dental calculus of the Western Siberia populations.
Mikhail Kotov, Yuliya Dombrovskaya, Anastasia Nikolaeva, Batyrbek Aslanov, Artemii Goncharov   +4 more
doaj   +1 more source

Multimodal Optical Imaging and Modulation with Simultaneous Electrophysiology Through Smart Dura in Non‐Human Primates

Advanced Science, EarlyView.
This study demonstrates multimodal integration in non‐human primates, combining large‐scale, high‐density electrophysiology using Smart Dura with optical techniques such as multiphoton imaging (MPI), photothrombotic lesioning, optical coherence tomography angiography (OCTA), wide‐field intrinsic signal optical imaging (ISOI), and optogenetics.
Nari Hong, Sergio Montalvo Vargo, Gaku Hatanaka, Zhaoyu Gong, Noah Stanis, Jasmine Zhou, Tiphaine Belloir, Ruikang K. Wang, Wyeth Bair, Maysamreza Chamanzar, Azadeh Yazdan‐Shahmorad   +10 more
wiley   +1 more source

Boston University Common Data Set 2017-2018 [PDF]

, 2018
This is the archive of common data sets of Boston University from 2017-2018, including general information, enrollment and persistence, first-time, first-year (freshman) admission, transfer admission, academic offerings and policies, student life, annual
Boston University
core  

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source