Results 131 to 140 of about 11,967 (299)

Citrullination of NF‐κB p65 by PAD2 as a Novel Therapeutic Target for Modulating Macrophage Polarization in Acute Lung Injury

Advanced Science, EarlyView.
Peptidyl arginine deiminase 2 (PAD2) plays a key role in regulating macrophage function in Pseudomonas aeruginosa‐induced acute lung injury (ALI). Using single‐cell RNA sequencing and proteomics, a new PAD2‐catalyzed citrullination site on NF‐κB p65 (171 Arginine), modulating macrophage polarization is identified.
Xin Yu, Yujing Song, Tao Dong, Wenlu Ouyang, Chao Quan, Liujiazi Shao, Leonard Barasa, Paul R. Thompson, Mao Zhang, Jianjie Ma, Katsuo Kurabayashi, Yongqing Li   +11 more
wiley   +1 more source

Different coding characteristics between flight and freezing in dorsal periaqueductal gray of mice during exposure to innate threats

Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 491-501, December 2022., 2022
Flight and freezing are two vital defensive behaviors in the process of avoiding natural enemies in mice. We investigated the neural activity in dPAG nuclei of mice under two defensive behaviors, and found different coding features between flight and freezing behaviors. Abstract Background Flight and freezing are two vital defensive behaviors that mice
Denghui Liu, Shouhao Li, Liqing Ren, Xinyu Liu, Xiaoyuan Li, Zhenlong Wang   +5 more
wiley   +1 more source

Prefrontal FGF1 Signaling is Required for Accumbal Deep Brain Stimulation Treatment of Addiction

Advanced Science, EarlyView.
This research delineates that a cortical‐accumbal pathway and local FGF1 signaling in the medial prefrontal cortex are critical for NAc‐DBS to be effective in altering morphine CPP. These findings demonstrate a top‐down motif to regulate the therapeutic effects of subcortical DBS on addiction and support the potential for addiction treatments involving
Wan‐Kun Gong, Xue Li, Le Wang, Qian Yang, Alix Tiran‐Cappello, Zhichao Liang, James Samsom, Quanying Liu, He Lin, Christelle Baunez, Fang Liu, Ti‐Fei Yuan   +11 more
wiley   +1 more source

Detection of plant-derived compounds in XIXth c. Dutch dental calculus [PDF]

, 2023
Louise Le Meillour
openalex   +1 more source

Viability of bacteria in dental calculus - A microbiological study

, 2010
NikeshN Moolya, Srinath Thakur, S. Ravindra, SwatiB Setty, Raghavendra D. Kulkarni, Kaverı Hallikeri   +5 more
openalex   +1 more source

Dental Floss, Calculus, and Jail [PDF]

, 2023
John A. Adam
openalex   +1 more source

Role of Testosterone Signaling in Microglia: A Potential Role for Sex‐Related Differences in Alzheimer's Disease

Advanced Science, EarlyView.
Testosterone enhances Aβ‐induced autophagy in microglia via the non‐genomic testosterone receptor GPRC6A, promoting Aβ clearance by suppressing ERK phosphorylation and inhibiting mTOR activation. In male 5xFAD mice, testicular removal reduces microglial autophagy and Aβ clearance, which is restored by testosterone.
Haiyan Du, Akiko Mizokami, Junjun Ni, Simeng Zhang, Yosuke Yamawaki, Tomomi Sano, Eijiro Jimi, Isei Tanida, Takashi Kanematsu   +8 more
wiley   +1 more source

The microscopic (optical and SEM) examination of dental calculus deposits (DCD). Potential interest in forensic anthropology of a bio-archaeological method

, 2010
Philippe Charlier, Isabelle Huynh‐Charlier, Olivia Muñoz, Michel Billard, Luc Brun, Geoffroy Lorin de la Grandmaison   +5 more
openalex   +2 more sources

The evidential value of dental calculus in the identification process [PDF]

, 2023
Dagmara Lisman, Joanna Drath, Grażyna Zielińska, Julia Zacharczuk, Jarosław Piątek, Thierry van de Wetering, Andrzej Ossowki   +6 more
openalex   +1 more source

Reprogramming Lung Redox Homeostasis by NIR Driven Ultra‐Small Pd Loaded Covalent Organic Framework Inhibits NF‐κB Pathway for Acute Lung Injury Immunotherapy

Advanced Science, EarlyView.
The strategy of ultra‐small Pd loaded covalent organic framework combined with NIR irradiation (TP@Pd+NIR) is developed to reprogram lung redox homeostasis for the synergistic enhancement of acute lung injury immunotherapy via ROS scavenging, M2 directional polarization, NF‐κB pathway inhibition as well as tissue repair acceleration.
Doudou Lei, Lin Liao, Tao Qin, Xiaoxuan Guan, Kunpeng Duan, Zhiwei Gao, Weiqian Jin, Mingjing Yin, Ke Zhang, Yan Liu, Yin Chen, Huyang Gao, Jiaxiao Li, Feifei Huang, Wenjing Liu, Chengde Xia, Bailei Wang, Hualin Huang, Shengqiu Lv, Qiang Zhi, Jiahao Huang, Ming Gao, Junyu Lu   +22 more
wiley   +1 more source