Results 121 to 130 of about 806,279 (404)

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

open access: yesAdvanced Healthcare Materials, EarlyView.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini   +2 more
wiley   +1 more source

Generation of a Single-Domain Antibody against Isolated Escherichia Coli that Causes Camel-Calf Death [PDF]

open access: diamond, 2021
A. Anouassi   +5 more
openalex   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

open access: yesAdvanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode   +16 more
wiley   +1 more source

Canadian dairy cattle veterinarian perspectives on calf welfare.

open access: yesJournal of Dairy Science, 2018
As advisors to dairy farmers, veterinarians are ideally positioned to influence the health of the dairy herd. Recent studies have demonstrated that dairy cattle veterinarians are also concerned about animal welfare, specifically on issues related to the ...
C. Sumner, M. V. Keyserlingk
semanticscholar   +1 more source

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

open access: yesAdvanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton   +2 more
wiley   +1 more source

Validation of MRC Centre MRI calf muscle fat fraction protocol as an outcome measure in CMT1A

open access: yesNeurology, 2018
Objective To translate the quantitative MRC Centre MRI protocol in Charcot-Marie-Tooth disease type 1A (CMT1A) to a second site; validate its responsiveness in an independent cohort; and test the benefit of participant stratification to increase outcome ...
J. Morrow   +11 more
semanticscholar   +1 more source

BLOC: Buildable and Linkable Organ on a Chip

open access: yesAdvanced Materials Technologies, EarlyView.
We developed a “Buildable and Linkable Organ on a Chip” (BLOC) that can construct diverse microphysiological systems (MPSs). The BLOC is standardized to the same size and has one of the functions of “Culture,” “Control,” or “Analysis.” Users can freely configure various MPSs, including developing perfusion, cytotoxicity analysis, and biochemical ...
Yusuke Kimura   +7 more
wiley   +1 more source

Production Practices of Arkansas Beef Cattle Producers [PDF]

open access: yes, 1998
This report contains information from a 1996 survey on production practices of Arkansas beef cattle producers. While several studies have been completed on the profitability of retained ownership of beef cattle, few empirical data are available on ...
Parsch, Lucas D., Popp, Michael P.
core   +2 more sources

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane   +4 more
wiley   +1 more source

Bovine intelligence for training horses [PDF]

open access: yes, 2007
A rail-mounted model of a small cow is to be used in the training of horses for camp-drafting contests. The paper concerns the addition of sensors and a strategy to enable the machine to respond to the proximity of the horse in a manner that will ...
Billingsley, John
core   +2 more sources

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