Results 241 to 250 of about 674,815 (312)

Deep Learning–Based Segmentation of Fetal Anatomical Structures in the First Trimester

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objectives To develop and evaluate an artificial intelligence (AI) system that automatically identifies and classifies the fetal structures in the first trimester. Method Over 20,000 ultrasound images from first‐trimester fetuses were prospectively collected from four university hospitals in the Republic of Korea.
Subeen Hong   +13 more
wiley   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella   +6 more
wiley   +1 more source

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

open access: yesJournal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá   +4 more
wiley   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Geomorphic Responses to Post‐Grazing Recovery and Stream Restoration in Semiarid Grassland Streams

open access: yesRiver Research and Applications, EarlyView.
ABSTRACT Semiarid grassland streams are sensitive to land use, climate, extreme discharges, and internal geomorphic thresholds that drive episodic erosion. Rooted in a process‐based philosophy and commonly applied to historically wood‐rich, beaver‐modified systems, low‐tech process‐based restoration using structures is increasingly being extended to ...
Owen Richardson, Ellen Wohl
wiley   +1 more source

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