Results 21 to 30 of about 325,061 (268)
The Spitsbergen population of bowhead whales (Balaena mysticetus) was harvested to near extinction during the whaling era. Here, we show possible signs of recovery of the population by reporting observations of two calves in the Scoresby Sund polynya in ...
Outi M. Tervo +4 more
doaj +1 more source
Mesothelioma in the Calf [PDF]
Three cases of mesothelioma in calves are described. Two were full-term foetuses, the other was 3 months old. There was ascites in all three. The tumours formed multiple, discrete nodules on the parietal and visceral peritoneum, and in the older calf also on the pleura. Lymph nodes were unaffected.
openaire +2 more sources
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Background The growth and health of young ruminants are regulated by their gut microbiome, which can have lifelong consequences. Compared with subjective grouping, phenotypic clustering might be a more comprehensive approach to revealing the relationship
Yimin Zhuang +15 more
doaj +1 more source
The decoupling of dairy production from cropland can increase environmental burdens and constrain the recycling of nutrients in manure in land-limited, purchased-feed-dependent large-scaled dairy farms. This study evaluated the environmental and marginal
Jingjun Wang +9 more
doaj +1 more source
Stall Sanitation Associated with Cryptosporidium sp. Infection on Calf and Cattle Farmer
Increasing the cattle population can increase the amount of the waste. Poor management of cage sanitation has the risk of causing a decrease in the health conditions of cattle farmers, such as: diarrhea, nausea, vomiting, and itching, as many as 50% of ...
Rafindra Ramadhani +6 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source

