Results 31 to 40 of about 317,965 (267)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Calf Pneumonia

Veterinary Clinics of North America: Food Animal Practice, 1985
Infectious calf pneumonia is a high-mortality pneumonia of housed dairy-type calves. Viruses are important etiologic agents and infection with bovine respiratory syncytial virus (RSV) and parainfluenza type 3 virus (PI-3 virus) may result in extensive, and sometimes fatal, lung damage. Respiratory viral infections are frequently followed by mycoplasmal
openaire   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

MicroRNA‐microbiota interactions: Emerging strategies for modulating intestinal homeostasis and enhancing host health

iMetaOmics
Long‐term artificial selection and environmental shifts have driven adaptive changes in both the host genome and the intestinal microbiota. The complex symbiotic relationship between these two has become essential for maintaining intestinal homeostasis ...
Tianle He, Jiaying Ma, Shuai Liu, Boyan Ma, Jingtao You, Jingjun Wang, Mengmeng Li, Wei Wang, Ya Jing Wang, Shengli Li, Zhijun Cao   +10 more
doaj   +1 more source

Disorders of acid-base balance promote rumen lipopolysaccharide biosynthesis in dairy cows by modulating the microbiome

Frontiers in Microbiology
IntroductionDisorders of acid-base balance in the rumen of dairy cows have a significant impact on their health and performance. However, the effect of transient differences in pH on susceptibility to subacute ruminal acidosis (SARA) and ...
Guobin Hou, Jingtao You, Yimin Zhuang, Duo Gao, Yiming Xu, Wen Jiang, Wen Jiang, Sumin Li, Xinjie Zhao, Tianyu Chen, Siyuan Zhang, Siyuan Zhang, Shuai Liu, Wei Wang, Shengli Li, Zhijun Cao   +15 more
doaj   +1 more source

Deep convolutional neural networks for the detection of diarrhea and respiratory disease in preweaning dairy calves using data from automated milk feeders

Journal of Dairy Science, 2022
: The objective of the current study was to develop a predictive model for calf disease detection in the preweaning period using data from automated milk feeders (AMF).
M.H. Ghaffari, A. Monneret, H.M. Hammon, C. Post, U. Müller, D. Frieten, C. Gerbert, G. Dusel, C. Koch   +8 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Invited review: An evaluation of EFSA opinion on calf welfare from a nutritional and management perspective

Journal of Dairy Science
: In March 2023, the European Food Safety Authority published a Scientific Opinion on Calf Welfare. This opinion was prepared in response to a request from the European Commission to provide an independent view on the welfare of calves that reflected the
J.D. Quigley
doaj   +1 more source

High energy diet of beef cows during gestation promoted growth performance of calves by improving placental nutrients transport

Frontiers in Veterinary Science, 2022
The aim of this study was to explore the effects of dietary energy level during gestation on growth performance and serum parameters in offspring using beef cattle as research objects.
Kun Kang, Lei Zeng, Jian Ma, Liyuan Shi, Rui Hu, Huawei Zou, Quanhui Peng, Lizhi Wang, Bai Xue, Zhisheng Wang   +9 more
doaj   +1 more source

CALF LYMPH. [PDF]

The Lancet, 1880
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openaire   +1 more source