Results 51 to 60 of about 52,118 (271)
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Mathematics, 2020 The use of probability-based panels that collect data via online or mixed-mode surveys has increased in the last few years as an answer to the growing concern with the quality of the data obtained with traditional survey modes.
Antonio Arcos +2 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2023 A suitable calibration sample set is extremely important to acquire an accurate spectral-based model for estimating soil organic matter (SOM). However, an unrepresentative calibration sample set was frequently collected due to the inappropriate samplings
Xibo Xu +5 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Semiparametric response model with nonignorable nonresponse [PDF]
, 2018 How to deal with nonignorable response is often a challenging problem encountered in statistical analysis with missing data. Parametric model assumption for the response mechanism is often made and there is no way to validate the model assumption with ...
Kim, Jae Kwang +2 more
core +3 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Evaluation of the synthetic estimators with non-respondent for small domain
HeliyonThe present work gives generalized form of the class of estimators if unit non-response is acquired in small domains. We have obtained indirect method like synthetic. It has provided specific instances where the proposed estimators are unbiased.
Abdullah Mohammed Alomair +1 more
doaj +1 more source
Sensors, 2020 Three-dimensional (3D) reconstruction is a useful technique for the documentation, characterization, and evaluation of small archeological objects. In this research, a comparison among different photogrammetric setups that use different lenses (macro and
Manuel Rodríguez-Martín +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source