Results 21 to 30 of about 7,106 (224)

Long-term dynamics of Norovirus transmission in Japan, 2005–2019 [PDF]

open access: yesPeerJ, 2021
Norovirus continues to evolve, adjusting its pathogenesis and transmissibility. In the present study, we systematically collected datasets on Norovirus outbreaks in Japan from 2005 to 2019 and analyzed time-dependent changes in the asymptomatic ratio ...
Megumi Misumi, Hiroshi Nishiura
doaj   +2 more sources

Protein Nucleotidylylation in +ssRNA Viruses

open access: yesViruses, 2021
Nucleotidylylation is a post-transcriptional modification important for replication in the picornavirus supergroup of RNA viruses, including members of the Caliciviridae, Coronaviridae, Picornaviridae and Potyviridae virus families.
Alice-Roza Eruera   +3 more
doaj   +1 more source

A little less aggregation a little more replication: Viral manipulation of stress granules

open access: yesWIREs RNA, Volume 14, Issue 1, January/February 2023., 2023
Viruses depend entirely on host machinery and therefore aim to conquer the host and defeat its defenses to co‐opt its resources for its own replication. Improved understanding of how viruses counteract host immune responses such as stress granule assembly, detailed here, will inform future antiviral therapeutic strategies.
Matthew J. Brownsword, Nicolas Locker
wiley   +1 more source

Viral Genome-Linked Protein (VPg) Is Essential for Translation Initiation of Rabbit Hemorrhagic Disease Virus (RHDV). [PDF]

open access: yesPLoS ONE, 2015
Rabbit hemorrhagic disease virus (RHDV), the causative agent of rabbit hemorrhagic disease, is an important member of the caliciviridae family. Currently, no suitable tissue culture system is available for proliferating RHDV, limiting the study of the ...
Jie Zhu   +7 more
doaj   +1 more source

Characterisation of the canine faecal virome in healthy dogs and dogs with acute diarrhoea using shotgun metagenomics. [PDF]

open access: yesPLoS ONE, 2017
The virome has been increasingly investigated in numerous animal species and in different sites of the body, facilitating the identification and discovery of a variety of viruses.
Paloma S Moreno   +5 more
doaj   +1 more source

A Novel Class of Norovirus Inhibitors Targeting the Viral Protease with Potent Antiviral Activity In Vitro and In Vivo

open access: yesViruses, 2021
Human noroviruses (HuNoVs) are the most common cause of viral gastroenteritis resulting annually in ~219,000 deaths and a societal cost of ~USD 60 billion, and no antivirals or vaccines are available.
Jana Van Dycke   +12 more
doaj   +1 more source

The Complexity of Swine Caliciviruses. A Mini Review on Genomic Diversity, Infection Diagnostics, World Prevalence and Pathogenicity

open access: yesPathogens, 2022
Caliciviruses are single stranded RNA viruses, non-enveloped structurally, that are implicated in the non-bacterial gastroenteritis in various mammal species.
Irit Davidson   +5 more
doaj   +1 more source

Caliciviridae

open access: yesIntervirology, 1980
The caliciviruses, as a proposed family Caliciviridae, have a distinct virion morphology with cup-shaped depressions on a spherical capsid surface. The viruses have single-stranded RNA, which has a molecular weight about 2.6 x 10(6) and is infectious. The RNA is covalently linked to a small protein. A single major polypeptide is found in the capsid.
F L, Schaffer   +10 more
openaire   +2 more sources

Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures [PDF]

open access: yes, 2017
Vesivirus 2117 is an adventitious agent that in 2009, was identified as a contaminant of CHO cells propagated in bioreactors at a pharmaceutical manufacturing plant belonging to Genzyme.
Bhella, David   +8 more
core   +1 more source

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