Results 11 to 20 of about 5,126 (132)
Treatment With Ruxolitinib and TAK-779 Enhances GII.17 Human Norovirus Replication and Enables Serial Passaging in Human Intestinal Enteroids. [PDF]
Genes CellsWe aimed to establish a simple method for GII.17 human norovirus (HuNoV) replication and serial passaging using wild‐type J2 human intestinal enteroids (HIEs). Treatment with ruxolitinib and TAK‐779, which target interferon and chemokine signaling, respectively, enhances viral replication and enables serial passaging of GII.17. ABSTRACT Human norovirus
Hiraishi E +4 more
europepmc +2 more sources
Characterization of a novel calicivirus causing systemic infection in atlantic salmon (Salmo salar L.): proposal for a new genus of caliciviridae. [PDF]
PLoS ONE, 2014 The Caliciviridae is a family of viruses infecting humans, a wide range of animals, birds and marine fish and mammals, resulting in a wide spectrum of diseases.
Aase B Mikalsen +6 more
doaj +1 more source
Discovery of a Novel Class of Norovirus Inhibitors with High Barrier of Resistance
Pharmaceuticals, 2021 Human noroviruses (HuNoVs) are the most common cause of viral gastroenteritis resulting in ~219,000 deaths annually and a societal cost of ~USD60 billion. There are no antivirals or vaccines available to treat and/or prevent HuNoV.
Jana Van Dycke +11 more
doaj +1 more source
Caliciviridae Other Than Noroviruses
Viruses, 2019 Besides noroviruses, the Caliciviridae family comprises four other accepted genera: Sapovirus, Lagovirus, Vesivirus, and Nebovirus. There are six new genera proposed: Recovirus, Valovirus, Bavovirus, Nacovirus, Minovirus, and Salovirus. All Caliciviridae
Ulrich Desselberger
doaj +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2010 INTRODUÇÃO: O norovírus foi recentemente identificado como o principal causador de surtos de gastroenterite aguda de origem não bacteriana em todo o mundo e está envolvido em episódios de origem alimentar.
Sofia Georgiadis +3 more
doaj +1 more source
Viruses, 2021 Acute gastroenteritis (AGE) is a major cause of morbidity and mortality worldwide, resulting in an estimated 440,571 deaths of children under age 5 annually. Rotavirus, norovirus, and sapovirus are leading causes of childhood AGE.
Mark R. Zweigart +5 more
doaj +1 more source
Calicivirus Non-structural Proteins: Potential Functions in Replication and Host Cell Manipulation
Frontiers in Microbiology, 2021 The Caliciviridae are a family of viruses with a single-stranded, non-segmented RNA genome of positive polarity. The ongoing discovery of caliciviruses has increased the number of genera in this family to 11 (Norovirus, Nebovirus, Sapovirus, Lagovirus ...
Elena Smertina +8 more
doaj +1 more source
The Fecal Virome of Children with Hand, Foot, and Mouth Disease that Tested PCR Negative for Pathogenic Enteroviruses. [PDF]
PLoS ONE, 2015 Hand, foot, and mouth disease (HFMD) affects infant and young children. A viral metagenomic approach was used to identify the eukaryotic viruses in fecal samples from 29 Thai children with clinical diagnosis of HFMD collected during the 2012 outbreak ...
Piyada Linsuwanon +5 more
doaj +1 more source
Preventing Foodborne Illness: Norovirus
EDIS, 2005 "Norovirus" was recently designated as the official genus name for the group of viruses previously described as “Norwalk-like viruses” (NLV). Noroviruses (family Caliciviridae, genus Norovirus) are a group of non-enveloped, single-stranded RNA viruses ...
Keith R. Schneider +3 more
doaj +5 more sources
Immune Response Modulation by Caliciviruses
Frontiers in Immunology, 2019 Noroviruses and Sapoviruses, classified in the Caliciviridae family, are small positive-stranded RNA viruses, considered nowadays the leading cause of acute gastroenteritis globally in both children and adults.
Yoatzin Peñaflor-Téllez +3 more
doaj +1 more source