Results 41 to 50 of about 5,383 (138)

Development and application of a SYBR Green RT-PCR for first line screening and quantification of porcine sapovirus infection [PDF]

open access: yes, 2012
BACKGROUND: Sapoviruses are single stranded positive sense RNA viruses belonging to the family Caliciviridae. The virus is detected in different species including the human and the porcine species as an enteric pathogen causing asymptomatic to ...
Hakze-Van der Honing, R.   +4 more
core   +4 more sources

Interferon-lambda: A potent regulator of intestinal viral infections [PDF]

open access: yes, 2017
Interferon-lambda (IFN-λ) is a recently described cytokine found to be of critical importance in innate immune regulation of intestinal viruses. Endogenous IFN-λ has potent antiviral effects and has been shown to control multiple intestinal viruses and ...
Baldridge, Megan T, Lee, Sanghyun
core   +3 more sources

Enteroviruses in Water: Epidemiology, Detection and Inactivation

open access: yesEnvironmental Microbiology, Volume 27, Issue 5, May 2025.
In this review, enterovirus presence and persistence in water are described. The epidemiology, detection and monitoring and control of enteroviruses are discussed. ABSTRACT Enteroviruses are small non‐enveloped RNA viruses commonly found in environmental water samples.
Corentin Morvan   +5 more
wiley   +1 more source

In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase [PDF]

open access: yes, 2018
Human norovirus causes approximately 219,000 deaths annually, yet there are currently no antivirals available. A virtual screening of commercially available drug-like compounds (~300,000) was performed on the suramin and PPNDS binding-sites of the ...
Ferla, Salvatore   +8 more
core   +3 more sources

Two Birds With One Stone: RNA Virus Strategies to Manipulate G3BP1 and Other Stress Granule Components

open access: yesWIREs RNA, Volume 16, Issue 2, March/April 2025.
Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus   +3 more
wiley   +1 more source

The ovarian cancer oncobiome. [PDF]

open access: yes, 2017
Humans and other mammals are colonized by microbial agents across the kingdom which can represent a unique microbiome pattern. Dysbiosis of the microbiome has been associated with pathology including cancer.
Alwine, J.C.   +7 more
core   +2 more sources

Establishment of a Novel Caco‐2‐Based Cell Culture System for Human Sapovirus Propagation

open access: yesGenes to Cells, Volume 30, Issue 2, March 2025.
We identified that both Caco‐2 cells and in‐house Caco‐2/Cas9 cells are susceptible to human sapovirus (HuSaV) infection. By performing two rounds of single‐cell cloning from Caco‐2/Cas9 cells, we successfully established a highly susceptible cell line, designated as Caco‐2MC.
Yuya Fukuda   +7 more
wiley   +1 more source

Porcine sapovirus replication is restricted by the type I interferon response in cell culture. [PDF]

open access: yes, 2015
Porcine sapovirus (PSaV) of the family Caliciviridae, is the only member of the genus Sapovirus with cell culture and reverse genetics systems. When combined with the piglet model, these approaches provide a system to understand the molecular basis of ...
Cho, Kyoung-Oh   +5 more
core   +3 more sources

Distribution of Microbial Contaminants of Minimally Processed Salads Produced in Tunisia: Need to Strengthen Good Hygiene Practices

open access: yesInternational Journal of Food Science, Volume 2025, Issue 1, 2025.
The microbiological safety of ready‐to‐eat (RTE) salads is considered as a major concern due to the absence of lethal treatments during processing. In this study, we aimed to investigate the microbiological quality of RTE salads commercialized in Tunisia and to determine the antibiotic resistance of isolated pathogens, in particular Staphylococcus ...
Widad Zernadji   +7 more
wiley   +1 more source

In Vitro Antiviral and Virucidal Activity of Ozone against Feline Calicivirus

open access: yesAnimals
The Caliciviridae family includes several viral pathogens of humans and animals, including norovirus (NoV), genus Norovirus, and feline calicivirus (FCV), genus Vesivirus.
Cristiana Catella   +10 more
doaj   +1 more source

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