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Apoptosis Activation During Lagovirus europaeus/GI.2 Infection in Rabbits [PDF]

open access: yesFrontiers in Microbiology, 2023
Rabbit Haemorrhagic Disease (RHD) is a severe disease caused by Lagovirus europaeus/GI.1 and GI.2. Immunological processes such as apoptosis are important factors involved in the pathogenesis of Rabbit Haemorrhagic Disease (RHD).
Rafał Hrynkiewicz   +2 more
exaly   +8 more sources

Occurrence of Lagovirus europaeus (Rabbit Hemorrhagic Disease Virus) in Domestic Rabbits in Southwestern Poland in 2019: Case Report. [PDF]

open access: yesMicrobiology Spectrum, 2022
Lagovirus europaeus (rabbit hemorrhagic disease virus [RHDV]) is a small, nonenveloped, single-stranded RNA virus that causes a severe, highly infectious, and fatal disease in rabbits (Oryctolagus cuniculus) called rabbit hemorrhagic disease (RHD). Since
Rafał Hrynkiewicz   +2 more
exaly   +6 more sources

MicroRNAs Participate in the Regulation of Apoptosis and Oxidative Stress-Related Gene Expression in Rabbits Infected With Lagovirus europaeus GI.1 and GI.2 Genotypes [PDF]

open access: yesFrontiers in Microbiology
MicroRNAs (miRs) are a group of small, 17–25 nucleotide, non-coding RNA that regulate gene expression at the post-transcriptional level. To date, little is known about the molecular signatures of regulatory interactions between miRs and apoptosis and ...
Andrzej Fitzner   +2 more
exaly   +5 more sources

Crosstalk between apoptosis and cytotoxic lymphocytes (CTLs) in the course of Lagovirus europaeus GI.1a infection in rabbits [PDF]

open access: yesJournal of Veterinary Research, 2023
Lagovirus europaeus is a single-stranded RNA virus causing an acute fatal disease in wild and domestic rabbits around the world. Studies have shown that the pivotal process impacting the immune response against the disease is apoptosis, registered mainly
Niedźwiedzka-Rystwej Paulina   +1 more
doaj   +4 more sources

Utilizing Molecular Epidemiology and Citizen Science for the Surveillance of Lagoviruses in Australia [PDF]

open access: yesViruses, 2023
Australia has multiple lagoviruses with differing pathogenicity. The circulation of these viruses was traditionally determined through opportunistic sampling events. In the lead up to the nationwide release of RHDVa-K5 (GI.1aP-GI.1a) in 2017, an existing
Nias Y. G. Peng   +14 more
doaj   +2 more sources

Digital PCR (dPCR) Quantification of miR-155-5p as a Potential Candidate for a Tissue Biomarker of Inflammation in Rabbits Infected with Lagovirus europaeus/Rabbit Hemorrhagic Disease Virus (RHDV) [PDF]

open access: yesViruses, 2023
MicroRNAs (miRNAs, miRs) are a group of small, 17–25 nucleotide, non-coding RNA sequences that, in their mature form, regulate gene expression at the post-transcriptional level.
Beata Hukowska-Szematowicz   +5 more
doaj   +2 more sources

Primer investigation of RIG-I-like receptors expression in virus infection with the acute character [PDF]

open access: yesInnate Immunity
This study investigates the expression of RIG-I-like receptors (RLRs) – RIG-I, MDA5, and LGP2 – in Lagovirus europaeus /GI.2 infections causing Rabbit Hemorrhagic Disease.
Filip Lewandowski   +4 more
doaj   +2 more sources

Genetic Characteristics and Phylogeographic Dynamics of Lagoviruses, 1988–2021 [PDF]

open access: yesViruses, 2023
Rabbit haemorrhagic disease virus (RHDV), European brown hare syndrome virus (EBHSV), rabbit calicivirus (RCV), and hare calicivirus (HaCV) belong to the genus Lagovirus of the Caliciviridae family that causes severe diseases in rabbits and several hare (
Pir Tariq Shah   +6 more
doaj   +2 more sources

Robust Innate Immunity of Young Rabbits Mediates Resistance to Rabbit Hemorrhagic Disease Caused by Lagovirus europaeus GI.1 but Not GI.2

open access: yesViruses, 2018
The rabbit caliciviruses Lagovirus europaeus GI.1 and GI.2 both cause acute necrotizing hepatitis in European rabbits (Oryctolagus cuniculus). Whilst GI.2 is highly virulent in both young and adult rabbits, rabbits younger than eight weeks of age are ...
Robyn N Hall   +2 more
exaly   +3 more sources

Detection of a New Recombinant Rabbit Hemorrhagic Disease Virus 2 in China and Development of Virus-like Particle-Based Vaccine [PDF]

open access: yesViruses
Rabbit hemorrhagic disease virus (RHDV) is a very virulent virus of the genus Lagovirus causing severe and fatal hepatitis in the European rabbit (Oryctolagus cuniculus). RHDV has two distinct genotypes: GI.1 (RHDV) and GI.2 (RHDV2). The first RHDV2/GI.2
Bo Hu   +5 more
doaj   +2 more sources

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