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Apoptosis activation during Lagovirus europaeus/GI.2 infection in rabbits [PDF]

open access: yesFrontiers in Microbiology, 2023
Rabbit Haemorrhagic Disease (RHD) is a severe disease caused by Lagovirus europaeus/GI.1 and GI.2. Immunological processes such as apoptosis are important factors involved in the pathogenesis of Rabbit Haemorrhagic Disease (RHD).
Rafał Hrynkiewicz   +2 more
exaly   +6 more sources

Occurrence of Lagovirus europaeus (Rabbit Hemorrhagic Disease Virus) in Domestic Rabbits in Southwestern Poland in 2019: Case Report [PDF]

open access: yesMicrobiology Spectrum, 2022
Lagovirus europaeus (rabbit hemorrhagic disease virus [RHDV]) is a small, nonenveloped, single-stranded RNA virus that causes a severe, highly infectious, and fatal disease in rabbits (Oryctolagus cuniculus) called rabbit hemorrhagic disease (RHD). Since
Ari Kauppinen   +2 more
exaly   +6 more sources

Crosstalk between apoptosis and cytotoxic lymphocytes (CTLs) in the course of Lagovirus europaeus GI.1a infection in rabbits [PDF]

open access: yesJournal of Veterinary Research, 2023
Lagovirus europaeus is a single-stranded RNA virus causing an acute fatal disease in wild and domestic rabbits around the world. Studies have shown that the pivotal process impacting the immune response against the disease is apoptosis, registered mainly
Niedźwiedzka-Rystwej Paulina   +1 more
doaj   +4 more sources

MicroRNAs participate in the regulation of apoptosis and oxidative stress-related gene expression in rabbits infected with Lagovirus europaeus GI.1 and GI.2 genotypes [PDF]

open access: yesFrontiers in Microbiology
MicroRNAs (miRs) are a group of small, 17–25 nucleotide, non-coding RNA that regulate gene expression at the post-transcriptional level. To date, little is known about the molecular signatures of regulatory interactions between miRs and apoptosis and ...
Andrzej Fitzner   +2 more
exaly   +4 more sources

Widespread occurrence of the non‐pathogenic hare calicivirus (HaCV Lagovirus GII.2) in captive‐reared and free‐living wild hares in Europe [PDF]

open access: yesTransboundary and Emerging Diseases, 2021
Abstract The Lagovirus genus comprises both pathogenic viruses as European brown hare syndrome virus (EBHSV‐ GII.1) and rabbit hemorrhagic disease viruses (RHDV‐GI.1 and RHDV2‐GI.2), that principally infect European brown hares (Lepus europeaus) and European rabbits (Oryctolagus cuniculus), respectively, causing severe necrotic hepatitis, spleen ...
Patrizia Cavadini   +2 more
exaly   +5 more sources

Utilizing Molecular Epidemiology and Citizen Science for the Surveillance of Lagoviruses in Australia [PDF]

open access: yesViruses, 2023
Australia has multiple lagoviruses with differing pathogenicity. The circulation of these viruses was traditionally determined through opportunistic sampling events. In the lead up to the nationwide release of RHDVa-K5 (GI.1aP-GI.1a) in 2017, an existing
Nias Y. G. Peng   +14 more
doaj   +2 more sources

Digital PCR (dPCR) Quantification of miR-155-5p as a Potential Candidate for a Tissue Biomarker of Inflammation in Rabbits Infected with Lagovirus europaeus/Rabbit Hemorrhagic Disease Virus (RHDV) [PDF]

open access: yesViruses, 2023
MicroRNAs (miRNAs, miRs) are a group of small, 17–25 nucleotide, non-coding RNA sequences that, in their mature form, regulate gene expression at the post-transcriptional level.
Beata Hukowska-Szematowicz   +5 more
doaj   +2 more sources

RHDV2 outbreak reduces survival and juvenile recruitment, causing European rabbit population collapse

open access: yesEcosphere
Infectious diseases can cause considerable mortality in vertebrate populations, especially when a new pathogen emerges. Quantifying the impact of diseases on wild populations and dissecting the underlying mechanisms requires longitudinal individual ...
Jérôme Letty   +7 more
doaj   +2 more sources

Primer investigation of RIG-I-like receptors expression in virus infection with the acute character [PDF]

open access: yesInnate Immunity
This study investigates the expression of RIG-I-like receptors (RLRs) – RIG-I, MDA5, and LGP2 – in Lagovirus europaeus /GI.2 infections causing Rabbit Hemorrhagic Disease.
Filip Lewandowski   +4 more
doaj   +2 more sources

Novel Recombinant Rabbit Hemorrhagic Disease Virus 2 (RHDV2) is Circulating in China within 12 Months after Original RHDV2 Arrival. [PDF]

open access: yesTransbound Emerg Dis, 2023
Rabbit hemorrhagic disease (RHD) causes lethal fulminant hepatitis in rabbits. Two different genotypes (GI.1 and GI.2) responsible for RHD are reported. GI.2 was first detected in France in 2010 and subsequently spread to other countries in Europe. In April 2020, GI.2 was detected in China.
Hu B   +9 more
europepmc   +2 more sources

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