Results 1 to 10 of about 3,058 (211)

The Baculovirus Expression System Expresses Chimeric RHDV VLPs as Bivalent Vaccine Candidates for Classic RHDV (GI.1) and RHDV2 (GI.2) [PDF]

Vaccines
Background: Rabbit hemorrhagic disease (RHD) is an acute, hemorrhagic and highly lethal infectious disease caused by rabbit hemorrhagic disease virus (RHDV), which causes huge economic losses to the rabbit breeding industry.
Yan Wang, Yiyang Fan, Ruixiang Bi, Yapeng Zhao, Wanning Gao, Derong Zhang, Jialin Bai   +6 more
doaj   +3 more sources

Immunogenicity of Multi-Target Chimeric RHDV Virus-Like Particles Delivering Foreign B-Cell Epitopes [PDF]

Vaccines, 2022
The rabbit hemorrhagic disease virus (RHDV) vaccine platform is a nanoparticle composed of 180 copies of the viral capsid protein, VP60, self-assembled into virus-like particles (VLPs).
María Zamora-Ceballos, Noelia Moreno, David Gil-Cantero, José R. Castón, Esther Blanco, Juan Bárcena   +5 more
doaj   +5 more sources

A Standardised Method to Quantify the Infectious Titre of Rabbit Haemorrhagic Disease Virus [PDF]

Viruses
Quantifying the infectious titre of preparations containing rabbit haemorrhagic disease virus (RHDV) is an essential virological technique during RHDV research.
Tiffany W. O’Connor, Damian Collins, Andrew J. Read, Paul M. Hick, Peter D. Kirkland   +4 more
doaj   +2 more sources

Characterization of the Maternally Derived Antibody Immunity against Rhdv-2 after Administration in Breeding Does of an Inactivated Vaccine

Vaccines, 2020
Inactivated strain-specific vaccines have been successfully used to control rabbit haemorrhagic disease (RHD) caused by RHDV-2 in the rabbit industry.
Massimiliano Baratelli, Joan Molist-Badiola, Alba Puigredon-Fontanet, Mariam Pascual, Oriol Boix, Francesc Xavier Mora-Igual, Michelle Woodward, Antonio Lavazza, Lorenzo Capucci   +8 more
doaj   +3 more sources

Molecular docking insights of Nigella sativa compounds as potential antiviral inhibitory agents against the replication-machinery proteins VPg and RdRP in rabbit hemorrhagic disease virus (RHDV) [PDF]

Virology Journal
The Rabbit Hemorrhagic Disease Virus (RHDV) represents a significant threat to rabbit populations globally, affecting both wild and domesticated rabbits, with mortality rates ranging from 50% to 90%.
Yousef R. Afifi, Tamer A. El-akkad, Omnia A. Badr, Shafik D. Ibrahim, Ahmed M. Serag   +4 more
doaj   +2 more sources

Optimising the Delivery of RHDV to Rabbits for Biocontrol: An Experimental Evaluation of Two Novel Methods of Virus Delivery [PDF]

Viruses, 2023
Rabbit haemorrhagic disease virus (RHDV) is established as a landscape-scale biocontrol that assists the management of invasive European rabbits and their impacts in both Australia and New Zealand.
Tshewang Dorji, Ridma M. J. Jayasingha Ellakkala Appuhamilage, Peter L. Bird, Nina Huang, Tiffany W. O’Connor, Kandarp K. Patel, Tanja Strive, Patrick L. Taggart   +7 more
doaj   +2 more sources

Chimeric RHDV Virus-Like Particles Displaying Foot-and-Mouth Disease Virus Epitopes Elicit Neutralizing Antibodies and Confer Partial Protection in Pigs

Vaccines, 2021
Currently there is a clear trend towards the establishment of virus-like particles (VLPs) as a powerful tool for vaccine development. VLPs are tunable nanoparticles that can be engineered to be used as platforms for multimeric display of foreign antigens.
Giselle Rangel, Juan Bárcena, Noelia Moreno, Carlos P. Mata, José R. Castón, Alí Alejo, Esther Blanco   +6 more
doaj   +3 more sources

Immunity against Lagovirus europaeus and the Impact of the Immunological Studies on Vaccination

Vaccines, 2021
In the early 1980s, a highly contagious viral hemorrhagic fever in rabbits (Oryctolagus cuniculus) emerged, causing a very high rate of mortality in these animals.
Claudia Müller, Rafał Hrynkiewicz, Dominika Bębnowska, Jaime Maldonado, Massimiliano Baratelli, Bernd Köllner, Paulina Niedźwiedzka-Rystwej   +6 more
doaj   +1 more source

Viral Genome-Linked Protein (VPg) Is Essential for Translation Initiation of Rabbit Hemorrhagic Disease Virus (RHDV). [PDF]

PLoS ONE, 2015
Rabbit hemorrhagic disease virus (RHDV), the causative agent of rabbit hemorrhagic disease, is an important member of the caliciviridae family. Currently, no suitable tissue culture system is available for proliferating RHDV, limiting the study of the ...
Jie Zhu, Binbin Wang, Qiuhong Miao, Yonggui Tan, Chuanfeng Li, Zongyan Chen, Huimin Guo, Guangqing Liu   +7 more
doaj   +1 more source

Chimeric VLPs Bearing VP60 from Two Serotypes of Rabbit Haemorrhagic Disease Virus Are Protective against Both Viruses

Vaccines, 2021
The VP60 capsid protein from rabbit haemorrhagic disease virus (RHDV), the causative agent of one of the most economically important disease in rabbits worldwide, forms virus-like particles (VLPs) when expressed using heterologous protein expression ...
Kevin P. Dalton, Carmen Alvarado, Edel Reytor, Maria del Carmen Nuñez, Ana Podadera, Diego Martínez-Alonso, Jose Manuel Martin Alonso, Ines Nicieza, Silvia Gómez-Sebastián, Romy M. Dalton, Francisco Parra, José M. Escribano   +11 more
doaj   +1 more source