Results 1 to 10 of about 1,394 (168)

The Baculovirus Expression System Expresses Chimeric RHDV VLPs as Bivalent Vaccine Candidates for Classic RHDV (GI.1) and RHDV2 (GI.2) [PDF]

Vaccines
Background: Rabbit hemorrhagic disease (RHD) is an acute, hemorrhagic and highly lethal infectious disease caused by rabbit hemorrhagic disease virus (RHDV), which causes huge economic losses to the rabbit breeding industry.
Yan Wang, Yiyang Fan, Ruixiang Bi, Yapeng Zhao, Wanning Gao, Derong Zhang, Jialin Bai   +6 more
doaj   +4 more sources

Molecular characterization of rabbit hemorrhagic disease virus type 2 and long-lasting protection conferred by a VLP-based vaccine [PDF]

BMC Veterinary Research
Background Rabbit hemorrhagic disease virus (RHDV) type 2 (GI.2) is an emerging pathogen genetically distinct from classic RHDV (GI.1). It can infect young, wild, and even vaccinated rabbits, and may also contract RHD.
Yanhui Wang, Peipei Qiao, Hongchao Wu, Xiaodan Tong, Tongyan Wang, Lu Wang, Yihang Yang, Xiaorui Su, Caihong Liu, Yalei Chen, Lulu Wang, Mengyue Wang, Xiangfeng Xi, Fang Wang, Wenqiang Pang, Yuxiu Liu, Kegong Tian   +16 more
doaj   +2 more sources

Immunogenicity of Multi-Target Chimeric RHDV Virus-Like Particles Delivering Foreign B-Cell Epitopes

Vaccines, 2022
The rabbit hemorrhagic disease virus (RHDV) vaccine platform is a nanoparticle composed of 180 copies of the viral capsid protein, VP60, self-assembled into virus-like particles (VLPs).
Juan Barcena, David Gil Cantero, Esther Blanco   +2 more
exaly   +3 more sources

A Standardised Method to Quantify the Infectious Titre of Rabbit Haemorrhagic Disease Virus [PDF]

Viruses
Quantifying the infectious titre of preparations containing rabbit haemorrhagic disease virus (RHDV) is an essential virological technique during RHDV research.
Tiffany W. O’Connor, Damian Collins, Andrew J. Read, Paul M. Hick, Peter D. Kirkland   +4 more
doaj   +2 more sources

Characterization of the Maternally Derived Antibody Immunity against Rhdv-2 after Administration in Breeding Does of an Inactivated Vaccine

Vaccines, 2020
Inactivated strain-specific vaccines have been successfully used to control rabbit haemorrhagic disease (RHD) caused by RHDV-2 in the rabbit industry.
Massimiliano Baratelli, Lorenzo Capucci, Michelle Woodward   +2 more
exaly   +3 more sources

Molecular docking insights of Nigella sativa compounds as potential antiviral inhibitory agents against the replication-machinery proteins VPg and RdRP in rabbit hemorrhagic disease virus (RHDV) [PDF]

Virology Journal
The Rabbit Hemorrhagic Disease Virus (RHDV) represents a significant threat to rabbit populations globally, affecting both wild and domesticated rabbits, with mortality rates ranging from 50% to 90%.
Yousef R. Afifi, Tamer A. El-akkad, Omnia A. Badr, Shafik D. Ibrahim, Ahmed M. Serag   +4 more
doaj   +2 more sources

Immunity against Lagovirus europaeus and the Impact of the Immunological Studies on Vaccination

Vaccines, 2021
In the early 1980s, a highly contagious viral hemorrhagic fever in rabbits (Oryctolagus cuniculus) emerged, causing a very high rate of mortality in these animals.
Claudia Müller, Rafał Hrynkiewicz, Dominika Bębnowska, Jaime Maldonado, Massimiliano Baratelli, Bernd Köllner, Paulina Niedźwiedzka-Rystwej   +6 more
doaj   +1 more source

Viral Genome-Linked Protein (VPg) Is Essential for Translation Initiation of Rabbit Hemorrhagic Disease Virus (RHDV). [PDF]

PLoS ONE, 2015
Rabbit hemorrhagic disease virus (RHDV), the causative agent of rabbit hemorrhagic disease, is an important member of the caliciviridae family. Currently, no suitable tissue culture system is available for proliferating RHDV, limiting the study of the ...
Jie Zhu, Binbin Wang, Qiuhong Miao, Yonggui Tan, Chuanfeng Li, Zongyan Chen, Huimin Guo, Guangqing Liu   +7 more
doaj   +1 more source

Chimeric VLPs Bearing VP60 from Two Serotypes of Rabbit Haemorrhagic Disease Virus Are Protective against Both Viruses

Vaccines, 2021
The VP60 capsid protein from rabbit haemorrhagic disease virus (RHDV), the causative agent of one of the most economically important disease in rabbits worldwide, forms virus-like particles (VLPs) when expressed using heterologous protein expression ...
Kevin P. Dalton, Carmen Alvarado, Edel Reytor, Maria del Carmen Nuñez, Ana Podadera, Diego Martínez-Alonso, Jose Manuel Martin Alonso, Ines Nicieza, Silvia Gómez-Sebastián, Romy M. Dalton, Francisco Parra, José M. Escribano   +11 more
doaj   +1 more source

Preparation of an inactivated oil emulsified vaccine against Rabbit Viral Hemorrhagic Disease [PDF]

Veterinary Medical Journal - Giza, 2011
An Experimental batch of an inactivated RHDV oil emulsified vaccine was prepared as water-in-oil emulsion with aqueous to oil ratio 1:2. The efficacy of the prepared vaccine was studied in vaccinated rabbits for one year post vaccination.
Salman A, Eman H, Abd El-Wanis A, Afaf A, Salwa EI- Assily   +4 more
doaj   +1 more source