Results 1 to 10 of about 828 (163)

Screening optimal DC-targeting peptide to enhance the immune efficacy of recombinant Lactobacillus expressing RHDV VP60 [PDF]

Virulence
Dendritic cells (DCs) present an ideal target for delivering immunogenic cargo due to their potent antigen-presenting capabilities. This targeting approach holds promise in vaccine development by enhancing the efficiency of antigen recognition and ...
Tian Xia, Xiao Lu, Deming Kong, Tiantian Guo, Yueyi Gao, Lingxiang Xin, Yanping Jiang, Xiaona Wang, Zhifu Shan, Jiaxuan Li, Han Zhou, Wen Cui, Xinyuan Qiao, Lijie Tang, Yijing Li, Li Wang   +15 more
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Diagnosis of a Rabbit Hemorrhagic Disease Virus 2 (RHDV2) and the Humoral Immune Protection Effect of VP60 Vaccine [PDF]

Current Issues in Molecular Biology, 2023
Rabbit hemorrhagic disease (RHD) is known as rabbit plague and hemorrhagic pneumonia. It is an acute, septic, and highly fatal infectious disease caused by the Lagovirus rabbit hemorrhagic disease virus (RHDV) in the family Caliciviridae that infects ...
Zhaoming Li, Kaimin Song, Yongzhen Du, Zhuanglong Zhang, Rupeng Fan, Pimiao Zheng, Jianzhu Liu   +6 more
doaj   +5 more sources

McHDV VP60 Virus-like Particles Elicit Protective Immunity Against Moschus chrysogaster Hemorrhagic Disease in Rabbits [PDF]

Pathogens
Moschus chrysogaster viral hemorrhagic disease (McVHD), caused by the Moschus chrysogaster hemorrhagic disease virus (McHDV), is an acute and highly fatal infectious disease of musk deer.
Yu Shao, Yudong Liu, Dong Huang, Qing Wang, Xiaoxiao He, Wenjing Zhao, Yunhai Zhao, Haiyun Ma, Xiaoyong Xing, Zhixiong Zhang, Shijun Bao   +10 more
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Sulfated Lactosyl Archaeol Archaeosome-Adjuvanted Vaccine Formulations Targeting Rabbit Hemorrhagic Disease Virus Are Immunogenic and Efficacious [PDF]

Vaccines, 2023
Vaccines play an important role in maintaining human and animal health worldwide. There is continued demand for effective and safe adjuvants capable of enhancing antigen-specific responses to a target pathogen.
Bassel Akache, Andrew J. Read, Renu Dudani, Blair A. Harrison, Dean Williams, Lise Deschatelets, Yimei Jia, Vandana Chandan, Felicity C. Stark, Gerard Agbayani, Shawn R. Makinen, Usha D. Hemraz, Edmond Lam, Sophie Régnier, Wei Zou, Peter D. Kirkland, Michael J. McCluskie   +16 more
doaj   +3 more sources

Rabbit Hemorrhagic Disease Virus VP60 Protein Expressed in Recombinant Swinepox Virus Self-Assembles Into Virus-Like Particles With Strong Immunogenicity in Rabbits [PDF]

Frontiers in Microbiology, 2022
Rabbit Hemorrhagic Disease (RHD) is an economically significant infectious disease of rabbits, and its infection causes severe losses in the meat and fur industry.
Changjin Liu, Min Lin, Huanyi Hu, Xiaolan Liu, Yanchao Bian, Xiaohua Huang, Xiaoxiang Li, Wenyang Yu, Feng Luo, Shunzhou Deng   +9 more
exaly   +4 more sources

The Baculovirus Expression System Expresses Chimeric RHDV VLPs as Bivalent Vaccine Candidates for Classic RHDV (GI.1) and RHDV2 (GI.2) [PDF]

Vaccines
Background: Rabbit hemorrhagic disease (RHD) is an acute, hemorrhagic and highly lethal infectious disease caused by rabbit hemorrhagic disease virus (RHDV), which causes huge economic losses to the rabbit breeding industry.
Yan Wang, Yiyang Fan, Ruixiang Bi, Yapeng Zhao, Wanning Gao, Derong Zhang, Jialin Bai   +6 more
doaj   +3 more sources

First report of GI.1aP-GI.2 recombinants of rabbit hemorrhagic disease virus in domestic rabbits in China [PDF]

Frontiers in Microbiology, 2023
The rabbit hemorrhagic disease virus 2 (RHDV2 or GI.2) is a highly contagious agent leading to lethal disease in rabbits. It frequently recombines with other Lagovirus genus, generating epidemical variants with high pathogenicity.
Yan Li, Deyan Du, Long Zhou, Liyin Su, Chengcheng You, Huai Zhang, Jifeng Yu, Lu Xiao, Jian Huang   +8 more
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Molecular characterization of rabbit hemorrhagic disease virus type 2 and long-lasting protection conferred by a VLP-based vaccine [PDF]

BMC Veterinary Research
Background Rabbit hemorrhagic disease virus (RHDV) type 2 (GI.2) is an emerging pathogen genetically distinct from classic RHDV (GI.1). It can infect young, wild, and even vaccinated rabbits, and may also contract RHD.
Yanhui Wang, Peipei Qiao, Hongchao Wu, Xiaodan Tong, Tongyan Wang, Lu Wang, Yihang Yang, Xiaorui Su, Caihong Liu, Yalei Chen, Lulu Wang, Mengyue Wang, Xiangfeng Xi, Fang Wang, Wenqiang Pang, Yuxiu Liu, Kegong Tian   +16 more
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Genetic Characteristics and Phylogeographic Dynamics of Lagoviruses, 1988–2021 [PDF]

Viruses, 2023
Rabbit haemorrhagic disease virus (RHDV), European brown hare syndrome virus (EBHSV), rabbit calicivirus (RCV), and hare calicivirus (HaCV) belong to the genus Lagovirus of the Caliciviridae family that causes severe diseases in rabbits and several hare (
Pir Tariq Shah, Amina Nawal Bahoussi, Caiting Yang, Guanhan Yao, Li Dong, Changxin Wu, Li Xing   +6 more
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Epitope mapping of a neutralizing antibody against rabbit hemorrhagic disease virus GI.2 [PDF]

Veterinary Research
In 2010, rabbit hemorrhagic disease virus (RHDV) GI.2 emerged, and unlike RHDV GI.1, it caused mortality in young rabbits, while existing vaccines were not fully protective.
Ana Podadera, Mila Leuthold, José Manuel Martín-Alonso, Rosa Casais, Angel Luis Álvarez, M. J. Lobo-Castañón, Francisco Parra, Kevin Paul Dalton   +7 more
doaj   +2 more sources