Genotyping of rabbit hemorrhagic disease virus detected in diseased rabbits in Egyptian Provinces by VP60 sequencing [PDF]
Veterinary World, 2020 Background and Aim: Rabbit hemorrhagic disease (RHD) is an economically important disorder of rabbits, where infection results in severe losses to the meat and fur industries.
Ahmed M. Erfan, Azhar G. Shalaby
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Polarisation of major histocompatibility complex II host genotype with pathogenesis of European Brown Hare syndrome virus. [PDF]
PLoS ONE, 2013 A study was conducted in order to determine the occurrence of European Brown Hare Syndrome virus (EBHSV) in Denmark and possible relation between disease pathogenesis and Major Histocompatibility Complex (MHC) host genotype.
Christos Iacovakis +18 more
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Immunogenicity of Multi-Target Chimeric RHDV Virus-Like Particles Delivering Foreign B-Cell Epitopes [PDF]
Vaccines, 2022 The rabbit hemorrhagic disease virus (RHDV) vaccine platform is a nanoparticle composed of 180 copies of the viral capsid protein, VP60, self-assembled into virus-like particles (VLPs).
María Zamora-Ceballos +5 more
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Precocious Eimeria magna transgenically expressing RHDV P2 subdomain induces immune responses in rabbits [PDF]
npj VaccinesRabbit coccidiosis and rabbit haemorrhagic disease (RHD) pose major threats to the rabbit industry, causing significant economic losses. Developing a multivalent vaccine to concurrently protect rabbits against Eimeria and RHDV infections would provide ...
Wenxuan Chen +8 more
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Protection of Rabbits against Rabbit Hemorrhagic Disease Virus by Immunization with the VP60 Protein Expressed in Plants with a Potyvirus-Based Vector [PDF]
Virology, 1997 A new plum pox potyvirus (PPV)-based vector has been constructed for the expression of full-length individual foreign proteins. The foreign sequences are cloned between the NIb replicase and capsid protein (CP) cistrons. The heterologous protein is split
Fernández-Fernández, María Rosario +5 more
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Serological characterisation of Lagovirus virus-like particles originating from native and mutated VP60 of rabbit haemorrhagic disease virus 2 and European brown hare syndrome virus [PDF]
Journal of Veterinary ResearchSince lagoviruses cannot be cultivated in vitro, using expression systems is an alternative and promising way of producing diagnostic viral antigens. It opens up their use as active immunogens for vaccine production.
Krejmer-Rąbalska Martyna +3 more
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Recombination between non-structural and structural genes as a mechanism of selection in lagoviruses: The evolutionary dead-end of an RHDV2 isolated from European hare [PDF]
Virus ResearchThe genus Lagovirus, belonging to the family Caliciviridae, emerged around the 1980s. It includes highly pathogenic species, rabbit hemorrhagic disease virus (RHDV/GI.1) and European brown hare syndrome virus (EBHSV/GII.1), which cause fatal hepatitis ...
Patrizia Cavadini +4 more
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Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography. [PDF]
PLoS Pathogens, 2013 Rabbit hemorrhagic disease, first described in China in 1984, causes hemorrhagic necrosis of the liver. Its etiological agent, rabbit hemorrhagic disease virus (RHDV), belongs to the Lagovirus genus in the family Caliciviridae.
Xue Wang +12 more
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Вопросы вирусологии, 2023 Introduction. Rabbit hemorrhagic disease is an acute highly contagious infection associated with two genotypes of pathogenic Lagovirus. Antibodies to major capsid protein (Vp60) are protective.
Aleksey N. Mukhin +6 more
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Confirmation of the Rabbit Hemorrhagic Disease Virus Type 2 (GI.2) Circulation in North Africa
Acta Veterinaria, 2022 Rabbit hemorrhagic disease (RHD) is a highly contagious viral disease that causes fatal acute hepatitis in domestic and wild lagomorphs. It has taken on major economic importance in countries like Morocco.
Saidi Aissa, Aboutaib Abdelouahed
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