Detection of positive selection in the major capsid protein VP60 of the rabbit haemorrhagic disease virus (RHDV) [PDF]
Virus Research, 2008 Mutations were analysed in the major capsid protein VP60 of the rabbit haemorrhagic disease virus (RHDV), a calicivirus responsible for high mortality rates in both wild and domestic European rabbits (Oryctolagus cuniculus). Likelihood of positive selection was estimated using the PAML software applied to 43 non-identical complete sequences of the ...
Pedro J Esteves +2 more
exaly +5 more sources
Phylogenetic Analysis of European Brown Hare Syndrome Virus Strains from Poland (1992–2004) [PDF]
Viruses, 2021 European brown hare syndrome (EBHS) is lethal to several species of free-living hares worldwide. The genetic characterization of its virus (EBHSV) strains in European circulation and epidemiological knowledge of EBHSV infections is not yet complete.
Andrzej Fitzner +5 more
doaj +3 more sources
Expression of the Viral Antigen VP60 in Transgenic Potatoes and its Effect on the Nutritional Composition of Tubers [PDF]
Food and Nutrition Sciences (Print), 2011 Recombinant plant-derived pharmaceuticals have been investigated for the last two decades and some products will soon be brought to market. Since veterinary pharmaceuticals seem to be the front-runners of plant-derived vaccines, we selected one model subunit vaccine, the structural capsid protein VP60 against rabbit haemorrhagic disease, and analyzed ...
Heike Mikschofsky +2 more
exaly +4 more sources
Recombinant Lactobacillus casei Expressing Capsid Protein VP60 can Serve as Vaccine Against Rabbit Hemorrhagic Disease Virus in Rabbits [PDF]
Vaccines, 2019 Rabbit hemorrhagic disease virus (RHDV) is the causative agent of rabbit hemorrhagic disease (RHD). RHD, characterized by hemorrhaging, liver necrosis, and high morbidity and mortality in rabbits and hares, causes severe economic losses in the rabbit ...
Li Wang +10 more
doaj +4 more sources
Successful oral prime‐immunization with VP60 from rabbit haemorrhagic disease virus produced in transgenic plants using different fusion strategies [PDF]
Plant Biotechnology Journal, 2005 SummaryExpression levels of vaccine antigens in transgenic plants have important consequences in their use as edible vaccines. The major structural protein VP60 from the rabbit haemorrhagic disease virus (RHDV) has been produced in transgenic plants using different strategies to compare its accumulation in plant tissues.
Gil Dones, Félix +4 more
core +7 more sources
Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography. [PDF]
PLoS Pathogens, 2013 Rabbit hemorrhagic disease, first described in China in 1984, causes hemorrhagic necrosis of the liver. Its etiological agent, rabbit hemorrhagic disease virus (RHDV), belongs to the Lagovirus genus in the family Caliciviridae.
Xue Wang +12 more
doaj +3 more sources
Genetic Characteristics and Phylogeographic Dynamics of Lagoviruses, 1988–2021 [PDF]
Viruses, 2023 Rabbit haemorrhagic disease virus (RHDV), European brown hare syndrome virus (EBHSV), rabbit calicivirus (RCV), and hare calicivirus (HaCV) belong to the genus Lagovirus of the Caliciviridae family that causes severe diseases in rabbits and several hare (
Pir Tariq Shah +6 more
doaj +2 more sources
Virus-like Particles Produced in the Baculovirus System Protect Hares from European Brown Hare Syndrome Virus (EBHSV) Infection [PDF]
VaccinesBackground/Objectives: European Brown Hare Syndrome (EBHS) is an acute and highly contagious viral disease of hares that causes considerable economic losses on wild and captive-reared hares.
Giulio Severi +13 more
doaj +2 more sources
Epitope mapping of a neutralizing antibody against rabbit hemorrhagic disease virus GI.2 [PDF]
Veterinary ResearchIn 2010, rabbit hemorrhagic disease virus (RHDV) GI.2 emerged, and unlike RHDV GI.1, it caused mortality in young rabbits, while existing vaccines were not fully protective.
Ana Podadera +7 more
doaj +2 more sources
Simultaneous Occurrence of Field Epidemics of Rabbit Hemorrhagic Disease (RHD) in Poland Due to the Co-Presence of Lagovirus europaeus GI.1 (RHDV)/GI.1a (RHDVa) and GI.2 (RHDV2) Genotypes [PDF]
VirusesThe highly fatal rabbit hemorrhagic disease (RHD) that first emerged in 1984 in China has spread worldwide and affects both domestic and wild rabbits. The disease was originally caused by RHD virus (Lagovirus europaeus, L.europaeus) of GI.1 genotype, but
Andrzej Fitzner +2 more
doaj +2 more sources