Genotyping of rabbit hemorrhagic disease virus detected in diseased rabbits in Egyptian Provinces by VP60 sequencing [PDF]
Background and Aim: Rabbit hemorrhagic disease (RHD) is an economically important disorder of rabbits, where infection results in severe losses to the meat and fur industries.
Ahmed M. Erfan, Azhar G. Shalaby
doaj +5 more sources
Chimeric VLPs Bearing VP60 from Two Serotypes of Rabbit Haemorrhagic Disease Virus Are Protective against Both Viruses [PDF]
The VP60 capsid protein from rabbit haemorrhagic disease virus (RHDV), the causative agent of one of the most economically important disease in rabbits worldwide, forms virus-like particles (VLPs) when expressed using heterologous protein expression ...
Kevin P. Dalton +11 more
doaj +6 more sources
Protection Against Rabbit Hemorrhagic Disease Virus Strains: Efficacy of a New Commercial Recombinant RHDV2 Capsid Protein VP60 Vaccine [PDF]
Background/Objectives: Rabbit hemorrhagic disease (RHD) is an incurable, highly contagious disease caused by different RHD virus (RHDV) strains, such as the coexisting RHDV2 and classical RHDV.
Mireia Fontseca +6 more
doaj +4 more sources
Recombinant Lactobacillus casei Expressing Capsid Protein VP60 can Serve as Vaccine Against Rabbit Hemorrhagic Disease Virus in Rabbits [PDF]
Rabbit hemorrhagic disease virus (RHDV) is the causative agent of rabbit hemorrhagic disease (RHD). RHD, characterized by hemorrhaging, liver necrosis, and high morbidity and mortality in rabbits and hares, causes severe economic losses in the rabbit ...
Li Wang +10 more
doaj +4 more sources
Expression of the Viral Antigen VP60 in Transgenic Potatoes and its Effect on the Nutritional Composition of Tubers [PDF]
Recombinant plant-derived pharmaceuticals have been investigated for the last two decades and some products will soon be brought to market. Since veterinary pharmaceuticals seem to be the front-runners of plant-derived vaccines, we selected one model subunit vaccine, the structural capsid protein VP60 against rabbit haemorrhagic disease, and analyzed ...
Heike Mikschofsky +12 more
openaire +3 more sources
Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography. [PDF]
Rabbit hemorrhagic disease, first described in China in 1984, causes hemorrhagic necrosis of the liver. Its etiological agent, rabbit hemorrhagic disease virus (RHDV), belongs to the Lagovirus genus in the family Caliciviridae.
Xue Wang +12 more
doaj +3 more sources
Successful oral prime‐immunization with VP60 from rabbit haemorrhagic disease virus produced in transgenic plants using different fusion strategies [PDF]
SummaryExpression levels of vaccine antigens in transgenic plants have important consequences in their use as edible vaccines. The major structural protein VP60 from the rabbit haemorrhagic disease virus (RHDV) has been produced in transgenic plants using different strategies to compare its accumulation in plant tissues.
Gil Dones, Félix +4 more
core +6 more sources
Recombinant VP60 in the form of virion-like particles as a potential vaccine against rabbit hemorrhagic disease virus. [PDF]
Rabbit hemorrhagic disease virus (RHDV) which causes a highly contagious disease of wild and domestic rabbits belongs to the family Caliciviridae. It is a small, positive single-stranded RNA virus with a genome of 7.5 kb and has a diameter of approximately 40 nm.
Beata Gromadzka +4 more
openaire +4 more sources
Virus-like Particles Produced in the Baculovirus System Protect Hares from European Brown Hare Syndrome Virus (EBHSV) Infection [PDF]
Background/Objectives: European Brown Hare Syndrome (EBHS) is an acute and highly contagious viral disease of hares that causes considerable economic losses on wild and captive-reared hares.
Giulio Severi +13 more
doaj +2 more sources
Simultaneous Occurrence of Field Epidemics of Rabbit Hemorrhagic Disease (RHD) in Poland Due to the Co-Presence of Lagovirus europaeus GI.1 (RHDV)/GI.1a (RHDVa) and GI.2 (RHDV2) Genotypes [PDF]
The highly fatal rabbit hemorrhagic disease (RHD) that first emerged in 1984 in China has spread worldwide and affects both domestic and wild rabbits. The disease was originally caused by RHD virus (Lagovirus europaeus, L.europaeus) of GI.1 genotype, but
Andrzej Fitzner +2 more
doaj +2 more sources

