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Systematic collection, annotation, and pattern analysis of viral vaccines in the VIOLIN vaccine knowledgebase [PDF]
BackgroundViral vaccines have been proven significant in protecting us against viral diseases such as COVID-19. To better understand and design viral vaccines, it is critical to systematically collect, annotate, and analyse various viral vaccines and ...
Anthony Huffman +8 more
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To Include or Occlude: Rational Engineering of HCV Vaccines for Humoral Immunity
Direct-acting antiviral agents have proven highly effective at treating existing hepatitis C infections but despite their availability most countries will not reach the World Health Organization targets for elimination of HCV by 2030.
Felicia Schlotthauer +2 more
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Membrane Chromatography-Based Downstream Processing for Cell-Culture Produced Influenza Vaccines
New influenza strains are constantly emerging, causing seasonal epidemics and raising concerns to the risk of a new global pandemic. Since vaccination is an effective method to prevent the spread of the disease and reduce its severity, the development of
Zeyu Yang +10 more
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The administration of viral vectored vaccines remains one of the most effective ways to respond to the ongoing novel coronavirus disease 2019 (COVID-19) pandemic.
Zeyu Yang +5 more
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Summary: Hyperimmune immunoglobulin (hCoV-2IG) generated from SARS-CoV-2 convalescent plasma (CP) are under evaluation in clinical trials. Here we explored the antibody epitope repertoire, and virus neutralizing capacity of six hCoV-2IG batches as well ...
Juanjie Tang +9 more
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The ongoing COVID-19 pandemic drew global attention to infectious diseases, attracting numerous resources for development of pandemic preparedness plans and vaccine platforms—technologies with robust manufacturing processes that can quickly be pivoted to
Julia Puppin Chaves Fulber +7 more
doaj +1 more source
In influenza vaccine development, Madin–Darby canine kidney (MDCK) cells provide multiple advantages, including large-scale production and egg independence. Several cell-based influenza vaccines have been approved worldwide.
Zhang Zhegang +19 more
doaj +1 more source
The COVID-19 pandemic has highlighted the need for efficient vaccine platforms that can rapidly be developed and manufactured on a large scale to immunize the population against emerging viruses.
Julia P. C. Fulber, Amine A. Kamen
doaj +1 more source
Avian influenza A(H7N9) epidemics have a fatality rate of approximately 40%. Previous studies reported that low pathogenic avian influenza (LPAI)-derived candidate vaccine viruses (CVVs) are poorly immunogenic.
Peter Radvak +10 more
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Capripoxvirus antibodies detection: Relationship between the two methods alpha and beta of virus neutralisation test [PDF]
Virus neutralisation test (VNT) of capripoxvirus (CaPVs) was studied to assess the post-vaccination (vaccine effectiveness) or post-infection antibodies level using two methods: alpha-VNT and beta-VNT which are generally carried out to measure the ...
Mohamed Hamidouche +6 more
doaj +1 more source

