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Intervention strategies for seasonal and emerging respiratory viruses with drugs and vaccines targeting viral surface glycoproteins [PDF]

open access: yes, 2021
Vaccines and therapeutics targeting viral surface glycoproteins are a major component of disease prevention for respiratory viral diseases. Over the years, vaccines have proven to be the most successful intervention for preventing disease.
Tripp, Ralph A.   +5 more
core   +1 more source

Long-Read High-Throughput Sequencing (HTS) Revealed That the Sf-Rhabdovirus X+ Genome Contains a 3.7 kb Internal Duplication

open access: yesViruses, 2023
We previously reported a novel rhabdovirus produced from the Spodoptera frugiperda Sf9 cell line, designated as Sf-rhabdovirus X+ since it contained a unique accessory gene X.
Hailun Ma, Trent J. Bosma, Arifa S. Khan
doaj   +1 more source

Is It Time for Vaccination to “Go Viral”?

open access: yesPediatric Infectious Disease Journal, 2016
To promote and sustain excellent vaccination coverage, while preserving the key core values of ethics, truth, transparency and trust, the vaccine community should adopt modern digital communication strategies. This article summarizes our views-as experts in multidisciplinary field of vaccinology (consisting of an anthropologist, a public health policy ...
Philip, Roy K.   +4 more
openaire   +4 more sources

Antibody affinity and cross-variant neutralization of SARS-CoV-2 Omicron BA.1, BA.2 and BA.3 following third mRNA vaccination

open access: yesNature Communications, 2022
Here the authors show that a third SARS-CoV-2 vaccination significantly boosts neutralizing antibodies against Omicron subvariants and that hybrid immunity (infection and vaccination) results in broader neutralization activity and cross-reactive antibody
Lorenza Bellusci   +6 more
doaj   +1 more source

Vaccine-Associated Enhanced Viral Disease: Implications for Viral Vaccine Development [PDF]

open access: yesBioDrugs, 2021
Vaccine-associated enhanced disease (VAED) is a serious barrier to attaining successful virus vaccines in human and veterinary medicine. VAED occurs as two different immunopathologies, antibody-dependent enhancement (ADE) and vaccine-associated hypersensitivity (VAH).
openaire   +2 more sources

Genome Editing Strategies to Protect Livestock from Viral Infections

open access: yes, 2021
The livestock industry is constantly threatened by viral disease outbreaks, including infections with zoonotic potential. While preventive vaccination is frequently applied, disease control and eradication also depend on strict biosecurity measures ...
Jenny-Helena Söllner   +2 more
core   +1 more source

Novel non-aqueous rotavirus vaccine: Formulated for thermostability and easy administration

open access: yesHuman Vaccines & Immunotherapeutics
Rotavirus vaccination has greatly reduced the number of deaths caused by the virus, lowering childhood mortality by an estimated 37% globally. Although low- and middle-income countries (LMIC) demonstrate reduced efficacy than high-income countries, the ...
John W. Langston   +10 more
doaj   +1 more source

MODELLING OF HEPATITIS E IN MINI-PIGS

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2017
Aim. Experimental reproduction of HEV-infection in mini-pigs and comparative analysis of virological and immunological characteristics of experimental infection. Materials and methods.
S. A. Gulyaev   +9 more
doaj   +1 more source

Universally Immune: How Infection Permissive Next Generation Influenza Vaccines May Affect Population Immunity and Viral Spread

open access: yes, 2021
Next generation influenza vaccines that target conserved epitopes are becoming a clinical reality but still have challenges to overcome. Universal next generation vaccines are considered a vital tool to combat future pandemic viruses and have the ...
Sophie A. Valkenburg   +3 more
core   +1 more source

The Immunological and Epidemiological Effectiveness of Pediatric Single-Dose Vaccination against Hepatitis A 9 to 11 Years after Its Implementation in the Tyva Republic, the Russian Federation

open access: yesVaccines
Since 2012, universal single-dose HAV vaccination in children aged 3 years and older has been implemented in the Tyva Republic, a region of the Russian Federation.
Maria A. Lopatukhina   +9 more
doaj   +1 more source

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