Results 61 to 70 of about 257,933 (304)

Advantages and Prospects of Tag/Catcher Mediated Antigen Display on Capsid-Like Particle-Based Vaccines [PDF]

, 2020
Capsid-like particles (CLPs) are multimeric, repetitive assemblies of recombinant viral capsid proteins, which are highly immunogenic due to their structural similarity to wild-type viruses.
Aves, Kara Lee, Kara-Lee Aves, Louise Goksøyr, Adam F. Sander, Sander, Adam F., Goksøyr, Louise   +5 more
core   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Validation of a Harmonized Enzyme-Linked-Lectin-Assay (ELLA-NI) Based Neuraminidase Inhibition Assay Standard Operating Procedure (SOP) for Quantification of N1 Influenza Antibodies and the Use of a Calibrator to Improve the Reproducibility of the ELLA-NI With Reverse Genetics Viral and Recombinant Neuraminidase Antigens: A FLUCOP Collaborative Study

Frontiers in Immunology, 2022
Current vaccination strategies against influenza focus on generating an antibody response against the viral haemagglutination surface protein, however there is increasing interest in neuraminidase (NA) as a target for vaccine development. A critical tool
Marie-Clotilde Bernard, Joanna Waldock, Sylvie Commandeur, Lea Strauß, Claudia Maria Trombetta, Serena Marchi, Fan Zhou, Serge van de Witte, Peter van Amsterdam, Sammy Ho, Katja Hoschler, Vladimir Lugovtsev, Jerry P. Weir, Emanuele Montomoli, Rebecca J. Cox, Othmar G. Engelhardt, Damien Friel, Ralf Wagner, Thierry Ollinger, Sophie Germain, Hanna Sediri-Schön   +20 more
doaj   +1 more source

Viral Vaccines of the Future

Pediatric Clinics of North America, 1990
Varicella vaccine seems close to licensure in the United States. It is likely to be recommended for routine use in healthy children, either administered singly or as a combination of MMR. Healthy children who have been immunized develop excellent antibody and cell-mediated responses to VZV in the absence of significant adverse effects, and they are ...
openaire   +2 more sources

Viral vaccines for farmed finfish [PDF]

VirusDisease, 2013
Over the past decade, aquaculture has grown at an average annual growth rate of approximately 6 % worldwide despite many challenges. Viral diseases are one of the major challenges that are threatening a sustainable growth of finfish farming globally.
Arun K, Dhar, Sanjib K, Manna, F C, Thomas Allnutt   +2 more
openaire   +2 more sources

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Viral Vaccines

, 2014
Since antiquity, humans have strived to find ways to prevent the suffering and mortality caused by infectious pathogens. No interventions in medical history have had a bigger impact on human health than the development of preventative vaccines against infectious diseases.
Marconi, P, Gavioli, R, Manservigi, R, CAPUTO, ANTONELLA, Ensoli, B.   +4 more
openaire   +3 more sources

Freeze-Drying of mRNA-LNPs Vaccines: A Review

Vaccines
The instability of mRNA vaccines presents significant challenges for their storage, transportation, and large-scale distribution, particularly in resource-limited countries.
MD Faizul Hussain Khan, Floriane Baudin, Ayyappasamy Sudalaiyadum Perumal, Amine A. Kamen   +3 more
doaj   +1 more source

Determination of antibodies to Caprine arthritis encephalitis virus in goats and sheep in some localities in Sudan

Journal of Advanced Veterinary and Animal Research, 2016
Objective: Caprine arthritis encephalitis (CAE) infection is existing worldwide causing economic loss in goat production. This work was conducted to investigate the prevalence of CAE in local and foreign goat breeds and sheep in different localities in ...
Wegdan Hassan Ali, Intisar Kamil Saeed, Shaza Mohammed Mutwakil, Omer A. Algezoli, Abdelgader Ballal Mohammed, Ihsan Hussein Ahmed, Sahar Mohammed Elhassan, Baraa Abdelaziz Ahmed, Rayan M. A. Asil, Saafass M. A. Alsarraj, Abdelmhmoud Atalmanan Abdelgader and Yahia Hassan Ali   +10 more
doaj   +1 more source

Establishing a Robust Manufacturing Platform for Recombinant Veterinary Vaccines: An Adenovirus-Vector Vaccine to Control Newcastle Disease Virus Infections of Poultry in Sub-Saharan Africa

Vaccines, 2020
Developing vaccine technology platforms to respond to pandemic threats or zoonotic diseases is a worldwide high priority. The risk of infectious diseases transmitted from wildlife and domestic animals to humans makes veterinary vaccination and animal ...
Omar Farnós, Esayas Gelaye, Khaled Trabelsi, Alice Bernier, Kumar Subramani, Héla Kallel, Martha Yami, Amine A. Kamen   +7 more
doaj   +1 more source