Results 51 to 60 of about 1,005,947 (300)
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Development of Robust Freeze-Drying Process for Long-Term Stability of rVSV-SARS-CoV-2 Vaccine
VirusesThe thermostability of vaccines, particularly enveloped viral vectored vaccines, remains a challenge to their delivery wherever needed. The freeze-drying of viral vectored vaccines is a promising approach but remains challenging due to the water removal ...
MD Faizul Hussain Khan +3 more
doaj +1 more source
Viral Vectors in Gene Therapy: Where Do We Stand in 2023?
, 2023 Viral vectors have been used for a broad spectrum of gene therapy for both acute and chronic diseases. In the context of cancer gene therapy, viral vectors expressing anti-tumor, toxic, suicide and immunostimulatory genes, such as cytokines and ...
Kenneth Lundstrom, Lundstrom, Kenneth
core +1 more source
Pediatric Clinics of North America, 1990 Varicella vaccine seems close to licensure in the United States. It is likely to be recommended for routine use in healthy children, either administered singly or as a combination of MMR. Healthy children who have been immunized develop excellent antibody and cell-mediated responses to VZV in the absence of significant adverse effects, and they are ...
openaire +2 more sources
Translating viral vaccines into immunity
Science, 2021 How adenoviral vaccines orchestrate adaptive immunity from innate responses is ...
Juno, Jennifer A., OConnor, Shelby L.
openaire +2 more sources
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Viral vaccines and their mode of action [PDF]
, 2002 Advantages and deficiency of different types of viral vaccines currently in use or in development in veterinary medicine are described. We emphasize the role of adjuvants in inactivated and genetically engineered vaccines as well as the role of marker ...
Sara Savic-Jevdjenic +3 more
core +2 more sources
Outside in – inside out. Creating focus on the patient – a vaccine company perspective
Human Vaccines & Immunotherapeutics, 2018 Involving patients in the development of medicines and vaccines should result in benefits to patients. The vaccine recipient is usually a healthy person.
Denis Sohy +7 more
doaj +1 more source
Viruses, 2020 African green monkey (AGM) spumaretroviruses have been less well-studied than other simian foamy viruses (SFVs). We report the biological and genomic characterization of SFVcae_FV2014, which was the first foamy virus isolated from an African green monkey
Sandra M. Fuentes +4 more
doaj +1 more source
iScience, 2022 Summary: Here we interrogate the factors responsible for SARS-CoV-2 breakthrough infections in a K18-hACE2 transgenic mouse model. We show that Delta and the closely related Kappa variant cause viral pneumonia and severe lung lesions in K18-hACE2 mice ...
Hyung-Joon Kwon +21 more
doaj +1 more source