Results 31 to 40 of about 792 (161)

Protection of Rabbits against Rabbit Hemorrhagic Disease Virus by Immunization with the VP60 Protein Expressed in Plants with a Potyvirus-Based Vector

Virology, 2001
A new plum pox potyvirus (PPV)-based vector has been constructed for the expression of full-length individual foreign proteins. The foreign sequences are cloned between the NIb replicase and capsid protein (CP) cistrons. The heterologous protein is split from the rest of the potyviral polyprotein by cleavage at the site that originally separated the ...
Fernández-Fernández, María Rosario, Mouriño, Mercedes, Rivera, José, Rodríguez, Francisco, Plana-Durán, Juan, García, Juan A.   +5 more
openaire   +4 more sources

Development of a peptide-generated antibody to rabbit hemorrhagic disease virus 2 VP60 and its immunohistochemical application in natural cases. [PDF]

J Vet Diagn Invest
Rabbit hemorrhagic disease virus 2 (RHDV2) has spread across the United States infecting and causing death in domestic and wild rabbits. Immunohistochemistry (IHC) would be a useful tool for the detection of RHDV2 antigen in tissues as it is inexpensive and readily achievable in most diagnostic laboratories.
Weyna AAW, Stilwell NK, Anders R, McHale B, McManamon R, Howerth EW.   +5 more
europepmc   +4 more sources

Nucleolin mediates the internalization of rabbit hemorrhagic disease virus through clathrin-dependent endocytosis.

PLoS Pathogens, 2018
Rabbit hemorrhagic disease virus (RHDV) is an important member of the Caliciviridae family and a highly lethal pathogen in rabbits. Although the cell receptor of RHDV has been identified, the mechanism underlying RHDV internalization remains unknown.
Jie Zhu, Qiuhong Miao, Jingyu Tang, Xiaoxue Wang, Dandan Dong, Teng Liu, Ruibin Qi, Zhibiao Yang, Guangqing Liu   +8 more
doaj   +2 more sources

Detection of rabbit Haemorrhagic disease virus 2 during the wild rabbit (Oryctolagus cuniculus) eradication from the Berlengas archipelago, Portugal

BMC Veterinary Research, 2017
Background In the regular wildlife monitoring action carried out in the summer of the past few years at the Berlenga Island, wild rabbits (Oryctolagus cuniculus) have been repeatedly found dead. However, the origin of those deaths was never investigated.
F.A. Abade dos Santos, C. Carvalho, Oliveira Nuno, J. J. Correia, M. Henriques, M. C. Peleteiro, M. Fevereiro, M. D. Duarte   +7 more
doaj   +2 more sources

Use of VP60 RT-PCR to overcome the limitation of haemagglutination inhibition diagnosis of rabbit viral haemorrhagic disease [PDF]

World Rabbit Science, 2011
This work was partially funded by the Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo, Egypt, and by Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Shakal, M.A., Khelfa, D.E.-D.G, Salman, O.G.A., Yousif, A.A., Salwa, E.-A.A   +4 more
openaire   +4 more sources

Serological characterisation of Lagovirus virus-like particles originating from native and mutated VP60 of rabbit haemorrhagic disease virus 2 and European brown hare syndrome virus [PDF]

Journal of Veterinary Research
Since lagoviruses cannot be cultivated in vitro, using expression systems is an alternative and promising way of producing diagnostic viral antigens. It opens up their use as active immunogens for vaccine production.
Krejmer-Rąbalska Martyna, Peplińska Marta, Szewczyk Bogusław, Fitzner Andrzej   +3 more
doaj   +2 more sources

Recombination between non-structural and structural genes as a mechanism of selection in lagoviruses: The evolutionary dead-end of an RHDV2 isolated from European hare [PDF]

Virus Research
The genus Lagovirus, belonging to the family Caliciviridae, emerged around the 1980s. It includes highly pathogenic species, rabbit hemorrhagic disease virus (RHDV/GI.1) and European brown hare syndrome virus (EBHSV/GII.1), which cause fatal hepatitis ...
Patrizia Cavadini, Tiziana Trogu, Roser Velarde, Antonio Lavazza, Lorenzo Capucci   +4 more
doaj   +2 more sources

Overcoming species barriers: an outbreak of Lagovirus europaeus GI.2/RHDV2 in an isolated population of mountain hares (Lepus timidus)

BMC Veterinary Research, 2018
Background Prior to 2010, the lagoviruses that cause rabbit hemorrhagic disease (RHD) in European rabbits (Oryctolagus cuniculus) and European brown hare syndrome (EBHS) in hares (Lepus spp.) were generally genus-specific.
Aleksija S. Neimanis, Harri Ahola, Ulrika Larsson Pettersson, Ana M. Lopes, Joana Abrantes, Siamak Zohari, Pedro J. Esteves, Dolores Gavier-Widén   +7 more
doaj   +2 more sources

Nicotiana benthamiana as a Source of Cowpea Mosaic Virus-Derived Particles That Specifically Package Designer RNAs. [PDF]

Plant Biotechnol J
ABSTRACT The coupling of replication and encapsidation in the bipartite plant virus, cowpea mosaic virus (CPMV), has been used to specifically incorporate designer RNA molecules into viral particles via transient expression in Nicotiana benthamiana. This is achieved by placing the desired RNA sequence between the 5′ and 3′ UTRs of CPMV RNA‐2 so that ...
Peyret H, Shah SN, Meshcheriakova Y, Jung JW, Saunders K, Lomonossoff GP.   +5 more
europepmc   +2 more sources

Novel Recombinant Rabbit Hemorrhagic Disease Virus 2 (RHDV2) is Circulating in China within 12 Months after Original RHDV2 Arrival. [PDF]

Transbound Emerg Dis, 2023
Rabbit hemorrhagic disease (RHD) causes lethal fulminant hepatitis in rabbits. Two different genotypes (GI.1 and GI.2) responsible for RHD are reported. GI.2 was first detected in France in 2010 and subsequently spread to other countries in Europe. In April 2020, GI.2 was detected in China.
Hu B, Fan Z, Qiu R, Chen M, Wei H, Song Y, Liu W, Xu W, Wang F, Wang F.   +9 more
europepmc   +2 more sources