Results 21 to 30 of about 828 (163)

Detection of a New Recombinant Rabbit Hemorrhagic Disease Virus 2 in China and Development of Virus-like Particle-Based Vaccine [PDF]

Viruses
Rabbit hemorrhagic disease virus (RHDV) is a very virulent virus of the genus Lagovirus causing severe and fatal hepatitis in the European rabbit (Oryctolagus cuniculus). RHDV has two distinct genotypes: GI.1 (RHDV) and GI.2 (RHDV2). The first RHDV2/GI.2
Bo Hu, Wenyu Dong, Yanhua Song, Zhiyu Fan, Patrizia Cavadini, Fang Wang   +5 more
doaj   +2 more sources

Pathological and virological insights from an outbreak of European brown hare syndrome in the Italian hare (Lepus corsicanus) [PDF]

Frontiers in Microbiology, 2023
European brown hare syndrome (EBHS) is a highly contagious and fatal viral disease, mainly affecting European brown hares (Lepus europaeus). The etiological agent, EBHS virus (EBHSV), belongs to the Lagovirus genus within the Caliciviridae family.
Mariagiovanna Domanico, Patrizia Cavadini, Roberto Nardini, Daniele Cecca, Giovanni Mastrandrea, Claudia Eleni, Valentina Galietta, Lorenzo Attili, Antonella Pizzarelli, Roberta Onorati, Cristina Amoruso, Donatella Stilli, Giulia Pacchiarotti, Francesca Merzoni, Andrea Caprioli, Ida Ricci, Antonio Battisti, Antonio Lavazza, Maria Teresa Scicluna   +18 more
doaj   +2 more sources

Immunogenicity in Rabbits of Virus-Like Particles from a Contemporary Rabbit Haemorrhagic Disease Virus Type 2 (GI.2/RHDV2/b) Isolated in The Netherlands

Viruses, 2019
Rabbit haemorrhagic disease virus (RHDV) type 2 (GI.2/RHDV2/b) is an emerging pathogen in wild rabbits and in domestic rabbits vaccinated against RHDV (GI.1).
Qiuhong Miao, Ruibing Qi, Luut Veldkamp, Jooske Ijzer, Marja L. Kik, Jie Zhu, Aoxing Tang, Dandan Dong, Yonghong Shi, Monique M. van Oers, Guangqing Liu, Gorben P. Pijlman   +11 more
doaj   +2 more sources

Two decades of occurrence of non-pathogenic rabbit lagoviruses in Italy and their genomic characterization [PDF]

Scientific Reports
Lagoviruses are viruses of the Caliciviridae family affecting lagomorphs. Both pathogenic and non-pathogenic lagoviruses affect the European rabbit (Oryctolagus cuniculus), and they are phylogenetically distinguished.
Patrizia Cavadini, Alice Vismarra, Francesca Merzoni, Vittoria Di Giovanni, Maria Beatrice Boniotti, Lorenzo Capucci, Antonio Lavazza   +6 more
doaj   +2 more sources

A novel reverse transcription recombinase polymerase amplification assay for rapid detection of GI.1 genotype of rabbit hemorrhagic disease virus [PDF]

Frontiers in Veterinary Science, 2023
Rabbit Viral Hemorrhagic Disease (RHD) is a highly contagious and fatal infection, resulting in considerable economic losses to the rabbit industry. Consequently, it is essential to develop a fast and accurate diagnostic method for RHDV GI.1.
Lianzhi Zhang, Qiaoya Zhao, Ye Tian, Yi Tang, Yixin Wang, Bing Huang   +5 more
doaj   +2 more sources

Molecular characterization of some isolates of rabbit viral hemorrhagic disease (VHD) in Egypt from 2014 to 2019 [PDF]

Journal of Advanced Veterinary and Animal Research, 2021
Objective: Rabbit viral hemorrhagic disease (VHD) is a transmittable and lethal viral illness of rabbits. In this study, genetic identification and genetic analysis of the rabbit hemorrhagic disease virus (RHDV) was made in three governorates in Egypt ...
Hanaa Awad El-Samadony, Hoda Mohammed Mekky, Aly Mohammed Ghetas, Aalaa Samir Saad   +3 more
doaj   +2 more sources

Immunogenicity of Multi-Target Chimeric RHDV Virus-Like Particles Delivering Foreign B-Cell Epitopes [PDF]

Vaccines, 2022
The rabbit hemorrhagic disease virus (RHDV) vaccine platform is a nanoparticle composed of 180 copies of the viral capsid protein, VP60, self-assembled into virus-like particles (VLPs).
María Zamora-Ceballos, Noelia Moreno, David Gil-Cantero, José R. Castón, Esther Blanco, Juan Bárcena   +5 more
doaj   +2 more sources

Nucleolin mediates the internalization of rabbit hemorrhagic disease virus through clathrin-dependent endocytosis. [PDF]

PLoS Pathogens, 2018
Rabbit hemorrhagic disease virus (RHDV) is an important member of the Caliciviridae family and a highly lethal pathogen in rabbits. Although the cell receptor of RHDV has been identified, the mechanism underlying RHDV internalization remains unknown.
Jie Zhu, Qiuhong Miao, Jingyu Tang, Xiaoxue Wang, Dandan Dong, Teng Liu, Ruibin Qi, Zhibiao Yang, Guangqing Liu   +8 more
doaj   +2 more sources

Precocious Eimeria magna transgenically expressing RHDV P2 subdomain induces immune responses in rabbits [PDF]

npj Vaccines
Rabbit coccidiosis and rabbit haemorrhagic disease (RHD) pose major threats to the rabbit industry, causing significant economic losses. Developing a multivalent vaccine to concurrently protect rabbits against Eimeria and RHDV infections would provide ...
Wenxuan Chen, Jingxia Suo, Jiahua Kong, Chunxia Lu, Xiaomin Ge, Fang Yu, Xinming Tang, Xun Suo, Xianyong Liu   +8 more
doaj   +2 more sources

Protection of Rabbits against Rabbit Hemorrhagic Disease Virus by Immunization with the VP60 Protein Expressed in Plants with a Potyvirus-Based Vector

Virology, 2001
A new plum pox potyvirus (PPV)-based vector has been constructed for the expression of full-length individual foreign proteins. The foreign sequences are cloned between the NIb replicase and capsid protein (CP) cistrons. The heterologous protein is split from the rest of the potyviral polyprotein by cleavage at the site that originally separated the ...
Fernández-Fernández, María Rosario, Mouriño, Mercedes, Rivera, José, Rodríguez, Francisco, Plana-Durán, Juan, García, Juan A.   +5 more
openaire   +4 more sources