Detection of a New Recombinant Rabbit Hemorrhagic Disease Virus 2 in China and Development of Virus-like Particle-Based Vaccine [PDF]
VirusesRabbit hemorrhagic disease virus (RHDV) is a very virulent virus of the genus Lagovirus causing severe and fatal hepatitis in the European rabbit (Oryctolagus cuniculus). RHDV has two distinct genotypes: GI.1 (RHDV) and GI.2 (RHDV2). The first RHDV2/GI.2
Bo Hu +5 more
doaj +2 more sources
Protection Against Rabbit Hemorrhagic Disease Virus Strains: Efficacy of a New Commercial Recombinant RHDV2 Capsid Protein VP60 Vaccine [PDF]
VaccinesBackground/Objectives: Rabbit hemorrhagic disease (RHD) is an incurable, highly contagious disease caused by different RHD virus (RHDV) strains, such as the coexisting RHDV2 and classical RHDV.
Mireia Fontseca +6 more
doaj +2 more sources
Pathological and virological insights from an outbreak of European brown hare syndrome in the Italian hare (Lepus corsicanus) [PDF]
Frontiers in Microbiology, 2023 European brown hare syndrome (EBHS) is a highly contagious and fatal viral disease, mainly affecting European brown hares (Lepus europaeus). The etiological agent, EBHS virus (EBHSV), belongs to the Lagovirus genus within the Caliciviridae family.
Mariagiovanna Domanico +18 more
doaj +2 more sources
Two decades of occurrence of non-pathogenic rabbit lagoviruses in Italy and their genomic characterization [PDF]
Scientific ReportsLagoviruses are viruses of the Caliciviridae family affecting lagomorphs. Both pathogenic and non-pathogenic lagoviruses affect the European rabbit (Oryctolagus cuniculus), and they are phylogenetically distinguished.
Patrizia Cavadini +6 more
doaj +2 more sources
A novel reverse transcription recombinase polymerase amplification assay for rapid detection of GI.1 genotype of rabbit hemorrhagic disease virus [PDF]
Frontiers in Veterinary Science, 2023 Rabbit Viral Hemorrhagic Disease (RHD) is a highly contagious and fatal infection, resulting in considerable economic losses to the rabbit industry. Consequently, it is essential to develop a fast and accurate diagnostic method for RHDV GI.1.
Lianzhi Zhang +5 more
doaj +2 more sources
Molecular characterization of some isolates of rabbit viral hemorrhagic disease (VHD) in Egypt from 2014 to 2019 [PDF]
Journal of Advanced Veterinary and Animal Research, 2021 Objective: Rabbit viral hemorrhagic disease (VHD) is a transmittable and lethal viral illness of rabbits. In this study, genetic identification and genetic analysis of the rabbit hemorrhagic disease virus (RHDV) was made in three governorates in Egypt ...
Hanaa Awad El-Samadony +3 more
doaj +2 more sources
Acta Biochimica Polonica, 2006 Rabbit hemorrhagic disease virus (RHDV) which causes a highly contagious disease of wild and domestic rabbits belongs to the family Caliciviridae. It is a small, positive single-stranded RNA virus with a genome of 7.5 kb and has a diameter of approximately 40 nm.
Beata, Gromadzka +4 more
openaire +4 more sources
Immunogenicity of Multi-Target Chimeric RHDV Virus-Like Particles Delivering Foreign B-Cell Epitopes [PDF]
Vaccines, 2022 The rabbit hemorrhagic disease virus (RHDV) vaccine platform is a nanoparticle composed of 180 copies of the viral capsid protein, VP60, self-assembled into virus-like particles (VLPs).
María Zamora-Ceballos +5 more
doaj +2 more sources
Viruses, 2019 Rabbit haemorrhagic disease virus (RHDV) type 2 (GI.2/RHDV2/b) is an emerging pathogen in wild rabbits and in domestic rabbits vaccinated against RHDV (GI.1).
Qiuhong Miao +11 more
doaj +2 more sources
Precocious Eimeria magna transgenically expressing RHDV P2 subdomain induces immune responses in rabbits [PDF]
npj VaccinesRabbit coccidiosis and rabbit haemorrhagic disease (RHD) pose major threats to the rabbit industry, causing significant economic losses. Developing a multivalent vaccine to concurrently protect rabbits against Eimeria and RHDV infections would provide ...
Wenxuan Chen +8 more
doaj +2 more sources