Results 1 to 10 of about 968 (131)

Characteristics of a new variant of rabbit haemorrhagic disease virus – RHDV2

Acta Biologica, 2019
RHD (Rabbit Haemorrhagic Disease) is an etiologic agent that causes viral haemorrhagic disease of rabbits, which is also referred to as rabbit plague. The desire to explore knowledge about this pathogen in the world results not only from its similarity ...
Dominika Bębnowska, Paulina Niedźwiedzka-Rystwej   +1 more
doaj   +1 more source

Recombinant Lactobacillus casei Expressing Capsid Protein VP60 can Serve as Vaccine Against Rabbit Hemorrhagic Disease Virus in Rabbits

Vaccines, 2019
Rabbit hemorrhagic disease virus (RHDV) is the causative agent of rabbit hemorrhagic disease (RHD). RHD, characterized by hemorrhaging, liver necrosis, and high morbidity and mortality in rabbits and hares, causes severe economic losses in the rabbit ...
Li Wang, Tian Xia, Tiantian Guo, Yi Ru, Yanping Jiang, Wen Cui, Han Zhou, Xinyuan Qiao, Lijie Tang, Yigang Xu, Yijing Li   +10 more
doaj   +1 more source

Chimeric RHDV Virus-Like Particles Displaying Foot-and-Mouth Disease Virus Epitopes Elicit Neutralizing Antibodies and Confer Partial Protection in Pigs

Vaccines, 2021
Currently there is a clear trend towards the establishment of virus-like particles (VLPs) as a powerful tool for vaccine development. VLPs are tunable nanoparticles that can be engineered to be used as platforms for multimeric display of foreign antigens.
Giselle Rangel, Juan Bárcena, Noelia Moreno, Carlos P. Mata, José R. Castón, Alí Alejo, Esther Blanco   +6 more
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Detection and Circulation of a Novel Rabbit Hemorrhagic Disease Virus in Australia

Emerging Infectious Diseases, 2018
The highly virulent rabbit hemorrhagic disease virus (RHDV) has been widely used in Australia and New Zealand since the mid-1990s to control wild rabbits, an invasive vertebrate pest in these countries.
Jackie E. Mahar, Andrew J. Read, Xingnian Gu, Nadya Urakova, Roslyn Mourant, Melissa Piper, Stéphanie Haboury, Edward C. Holmes, Tanja Strive, Robyn N. Hall   +9 more
doaj   +1 more source

A pandemic strain of calicivirus threatens rabbit industries in the Americas

Virology Journal, 2007
Rabbit Hemorrhagic Disease (RHD) is a severe acute viral disease specifically affecting the European rabbit Oryctolagus cuniculus. As the European rabbit is the predominant species of domestic rabbit throughout the world, RHD contributes towards ...
Botti Giuliana, Ward Gordon B, Neilan John G, Burrage Thomas G, Moran Karen E, Lu Zhiqiang, Mohamed Fawzi M, Behan Shawn C, McIntosh Michael T, Capucci Lorenzo, Metwally Samia A   +10 more
doaj   +1 more source

Sulfated Lactosyl Archaeol Archaeosome-Adjuvanted Vaccine Formulations Targeting Rabbit Hemorrhagic Disease Virus Are Immunogenic and Efficacious

Vaccines, 2023
Vaccines play an important role in maintaining human and animal health worldwide. There is continued demand for effective and safe adjuvants capable of enhancing antigen-specific responses to a target pathogen.
Bassel Akache, Andrew J. Read, Renu Dudani, Blair A. Harrison, Dean Williams, Lise Deschatelets, Yimei Jia, Vandana Chandan, Felicity C. Stark, Gerard Agbayani, Shawn R. Makinen, Usha D. Hemraz, Edmond Lam, Sophie Régnier, Wei Zou, Peter D. Kirkland, Michael J. McCluskie   +16 more
doaj   +1 more source

Immunogenicity of Multi-Target Chimeric RHDV Virus-Like Particles Delivering Foreign B-Cell Epitopes

Vaccines, 2022
The rabbit hemorrhagic disease virus (RHDV) vaccine platform is a nanoparticle composed of 180 copies of the viral capsid protein, VP60, self-assembled into virus-like particles (VLPs).
María Zamora-Ceballos, Noelia Moreno, David Gil-Cantero, José R. Castón, Esther Blanco, Juan Bárcena   +5 more
doaj   +1 more source

Facts about Wildlife Diseases: Rabbit Hemorrhagic Disease Virus Serotype 2 (RHDV2)

EDIS, 2022
This publication provides information on rabbit hemorrhagic disease virus serotype 2 (RHDV2) and discusses infection, clinical signs, treatment, prevention, and reporting. Written by Catherine E. Dixon and Juan M.
Catherine E. Dixon, Juan M. Campos Krauer   +1 more
doaj   +3 more sources

Nucleolin mediates the internalization of rabbit hemorrhagic disease virus through clathrin-dependent endocytosis.

PLoS Pathogens, 2018
Rabbit hemorrhagic disease virus (RHDV) is an important member of the Caliciviridae family and a highly lethal pathogen in rabbits. Although the cell receptor of RHDV has been identified, the mechanism underlying RHDV internalization remains unknown.
Jie Zhu, Qiuhong Miao, Jingyu Tang, Xiaoxue Wang, Dandan Dong, Teng Liu, Ruibin Qi, Zhibiao Yang, Guangqing Liu   +8 more
doaj   +1 more source

Mannosylation of virus-like particles enhances internalization by antigen presenting cells. [PDF]

PLoS ONE, 2014
Internalization of peptides by antigen presenting cells is crucial for the initiation of the adaptive immune response. Mannosylation has been demonstrated to enhance antigen uptake through mannose receptors, leading to improved immune responses.
Farah Al-Barwani, Sarah L Young, Margaret A Baird, David S Larsen, Vernon K Ward   +4 more
doaj   +1 more source