Inhibition of interferon signaling improves rabbit calicivirus replication in biliary organoid cultures [PDF]
Journal of VirologyThe Rabbit hemorrhagic disease virus (RHDV) was discovered 40 years ago. This highly pathogenic virus threatens the integrity of ecosystems in the European rabbit’s native range, while in Australia, it is used as a biocontrol tool to manage overabundant ...
Elena Smertina +7 more
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The Baculovirus Expression System Expresses Chimeric RHDV VLPs as Bivalent Vaccine Candidates for Classic RHDV (GI.1) and RHDV2 (GI.2) [PDF]
VaccinesBackground: Rabbit hemorrhagic disease (RHD) is an acute, hemorrhagic and highly lethal infectious disease caused by rabbit hemorrhagic disease virus (RHDV), which causes huge economic losses to the rabbit breeding industry.
Yan Wang +6 more
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Codon optimization of the rabbit hemorrhagic disease virus (RHDV) capsid gene leads to increased gene expression in Spodoptera frugiperda 9 (Sf9) cells. [PDF]
J Vet Sci, 2013 Rabbit hemorrhagic disease (RHD) is contagious and highly lethal. Commercial vaccines against RHD are produced from the livers of experimentally infected rabbits. Although several groups have reported that recombinant subunit vaccines against rabbit hemorrhagic disease virus (RHDV) are promising, application of the vaccines has been restricted due to ...
Gao J, Meng C, Chen Z, Li C, Liu G.
europepmc +3 more sources
RNAi Inhibition of Rabbit Hemorrhagic Disease Virus (RHDV) Gene Expression in CHO Cell Line [PDF]
مجلة جامعة النجاح للأبحاث العلوم الطبيعية, 2008 Rabbit hemorrhagic disease virus (RHDV) causes great losses and is life threatening to both wild and domestic rabbits. This work represents the first step toward production of transgenic rabbits resistant to RHDV by RNAi through the inhibition of ...
Bilal Ghareeb
doaj +2 more sources
Rabbit Hemorrhagic Disease Virus 2 (RHDV2; GI.2) Is Replacing Endemic Strains of RHDV in the Australian Landscape within 18 Months of Its Arrival [PDF]
Journal of Virology, 2018 ABSTRACT Rabbit hemorrhagic disease virus 2 (RHDV2; Lagovirus GI.2) is a pathogenic calicivirus that affects European rabbits ( Oryctolagus cuniculus ) and various hare ( Lepus ) species.
Tarnya Cox +2 more
exaly +4 more sources
Virus Research, 1992 Purified preparations of the Spanish field isolate of rabbit hemorrhagic disease virus AST/89 were found to contain the plus-stranded genomic RNA of more than 7.4 kilobases (kb) and large amounts of a subgenomic mRNA of 2.4 kb. The smaller RNA was translated in vitro and shown to code for a 60 kDa protein which was immunoprecipitated using anti-RHDV as
Rosa Casais +2 more
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Case series: Four fatal rabbit hemorrhagic disease virus infections in urban pet rabbits
Frontiers in Veterinary Science, 2023 Four pet rabbits (Oryctolagus cuniculus cuniculus) diagnosed with a fatal infection by rabbit hemorrhagic disease virus (RHDV GI.2) were identified in the same week and further investigated.
Filipe Fontes Pinto +11 more
doaj +3 more sources
Two decades of occurrence of non-pathogenic rabbit lagoviruses in Italy and their genomic characterization [PDF]
Scientific ReportsLagoviruses are viruses of the Caliciviridae family affecting lagomorphs. Both pathogenic and non-pathogenic lagoviruses affect the European rabbit (Oryctolagus cuniculus), and they are phylogenetically distinguished.
Patrizia Cavadini +6 more
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Detection of a New Recombinant Rabbit Hemorrhagic Disease Virus 2 in China and Development of Virus-like Particle-Based Vaccine [PDF]
VirusesRabbit hemorrhagic disease virus (RHDV) is a very virulent virus of the genus Lagovirus causing severe and fatal hepatitis in the European rabbit (Oryctolagus cuniculus). RHDV has two distinct genotypes: GI.1 (RHDV) and GI.2 (RHDV2). The first RHDV2/GI.2
Bo Hu +5 more
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Epitope mapping of a neutralizing antibody against rabbit hemorrhagic disease virus GI.2 [PDF]
Veterinary ResearchIn 2010, rabbit hemorrhagic disease virus (RHDV) GI.2 emerged, and unlike RHDV GI.1, it caused mortality in young rabbits, while existing vaccines were not fully protective.
Ana Podadera +7 more
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